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Please login or sign up for a free trial to access the full content. Variation 2: From Hydroxylamines

DOI: 10.1055/sos-SD-029-00649

Merino, P.Science of Synthesis, (200729709.

The reactivity of the hydroxy group of hydroxylamine is often very similar to that observed for a primary alcohol. Thus, the cyclic aromatic hydroxylamine 17 undergoes reaction with an excess of 2-methoxypropene in the presence of catalytic 4-toluenesulfonic acid to give, after 10 minutes, the NO protected hydroxylamine 18 (Scheme 7).[‌8‌]

Meeeee 8 Meeeeeeee ee ee M-(Meeeeeeeeeeee)eeeee[‌8‌]

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Meeeee 8 Meeeeeeee ee ee M-(Meeeeeeeeeeeeeeee)eeeeeeeeeeeee[‌8‌]

Me eee eeeeeee ee eeeeeeeee eeeeeeeeeee eee eeeeeeee eeeee 8 eeee ee ee ee eeeeeeeeee, eeeeeeee eeeeee eeeeee (8888%) eee eeeeeeee. Meeeeee eeeeeee eeeeeee ee eeeeeeeeeee ee eee eeeeeeee ee eee eeeeeee-eeeeeee eeeeeee 88, eeeeeeeee ee eeeeeeeeee eeee ee-eeee-eeeee eeeeeeee (Meeeee 8).[‌88‌] Mee eeeeeeee ee eeeeeeeeee eeeeeeeeeeee, eeee eeeeeee ee 88 eeeee eeeeee ee eeeee eeeeeee.

Meeeee 8 Meeeeeeee ee ee M-(Meeeeeeeeeeeeee-8-ee)eeeeeeeeeeeee[‌88‌]

Mee M-eeeeeeeeeeeeee 88 ee eeeeeeeee ee eeeeeeee eeee eeeeeeeeeeee eeeeee eeeee eeeee eeeee eeeeeeeeee (Meeeee 88).[‌88‌] Mee eeeeeeee eeeeeeee ee eeee eeeeeeeeeee ee eeee 88 ee eeeeee eeeeeeeeeeee eeeee.

Meeeee 88 Meeeeeeee ee e 8-(Meeeeeeeeeeeee)-8M-eeeeeee[‌88‌]

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8-(8,8-Meeeeeeee-8-{[(eeeeeeeeee-8M-eeeee-8-eeeee)eeeee]eeeeee}eeeeeee)eeeeeeee Meee (88):[‌88‌]

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