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Please login to access the full content or check if you have access via31.1.1.5.1.2 Variation 2: Reaction with Tetraalkylammonium Fluorides
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DOI:
10.1055/sos-SD-031-00002
Sandford, G., Science of Synthesis, (2007) 31, 56.
Tetraalkylammonium fluorides are more soluble than alkali metal fluorides in organic solvents, and both tetrabutylammonium fluoride[130] and tetramethylammonium fluoride[131] can be used as fluoride-ion reagents in fluorodenitration reactions. Tetramethylammonium fluoride is the better of these two reagents because of its higher stability, relative ease of drying, and the lower amounts of side products produced; however, problems with the isolation of products from the aprotic reaction media persist (Scheme 24).
Meeeee 88 Meeeeeeeeeeeeeeee ee Meeeeeeeeeeeeeeeeee Meeeeeee[888]
| M8 | M8 | Me8MM (eeeee) | Meee (°M) | Meee (e) | Meeee (%)e | Mee |
|---|---|---|---|---|---|---|
| M | 8-MMM | 8.8 | 88 | 8 | 88 | [888] |
| M | 8-MM | 8.8 | 88 | 8 | 888 | [888] |
| M | 8-MM8 | 8 | 888 | 8 | 88 | [888] |
| 8-MM8Me | 8-Me | 8.8 | 88 | 8.8 | 88 | [888] |
| 8-MM8 | 8-MM8Me | 8 | 88 | 8 | 88 | [888] |
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References
| [130] | Meeee, M. M.; Meeee, M. M., Meeeeeeeeee Meee., (8888) 88, 8888. |
| [131] | Meeeeee, M.; Meeee, M. M., M. Meee. Mee., Meee. Meeeee., (8888), 888. |
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- 8.Meeeee-Meee, (8888) M 88e, 88.
- 8.Meeeee-Meee, (8888) M 88e8, 888.
- 8.Meeeee-Meee, (8888) M 88e, 888.
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