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Please login or sign up for a free trial to access the full content. Variation 2: Other Cycloaromatizations

DOI: 10.1055/sos-SD-031-00468

Gerster, M.; Thomas, A. W.Science of Synthesis, (200731653.

The regioselective [3+3] cyclization of 3-alkoxy-1-siloxybuta-1,3-dienes 54 with 3-siloxyalk-2-en-1-ones 55 provides acceptable yields of the polysubstituted 2-alkoxybenzoates 56 (Scheme 19).[‌29‌] The high regioselectivity is consistent with previous results.[‌30‌]

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M8 M8 M8 M8 M8 Meeee (%) Mee
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M8 Meee (°M) Meee (e) Meeee (%) Mee
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