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Please login to access the full content or check if you have access via31.21.1.1.5 Variation 5: Using Nitric Acid in an Ionic Liquid
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Aitken, K. M.; Aitken, R. A., Science of Synthesis, (2007) 31, 1190.
Nitration of benzene (to give 22), chlorobenzene, toluene, biphenyl, and anisole proceeds in 99–100% yields in 1-decyl-3-methylimidazolium trifluoromethanesulfonate or 1-butyl-3-methylimidazolium trifluoromethanesulfonate (Scheme 8).[45] The choice of ionic liquid is crucial, as changing the anion gives rise to completely different reactivity; for example, halides lead to ring halogenation.
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References
| [45] | Meeee, M. M.; Meeeeee, M. M.; Meeeee, M. M., Mee. Meee., (8888) 8, 888. |
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