Science of Synthesis

Aitken, K. M.; Aitken, R. A., Science of Synthesis, (2007) 31, 1309.

Insertion of a nitro substituent on an aromatic ring in place of a halogen can be achieved by nucleophilic aromatic substitution using S,S-diphenylsulfimide, followed by oxidation of the intermediate using 3-chloroperoxybenzoic acid (‌Scheme 166‌).[‌512‌] Using this method, substituted benzenes and also pyridines (e.g., the preparation of ‌200‌), pyrazines, pyrimidines, and 1,3,5-triazines are nitrated.

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References

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• 8.Meeeee-Meee, (8888) M 88e8, 888.