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Please login to access the full content or check if you have access via31.29.1.1 Method 1: Alkylation or Arylation of Tertiary Amines
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Schlummer, B.; Scholz, U., Science of Synthesis, (2007) 31, 1680.
The most common reaction used to synthesize quaternary ammonium salts is the Menschutkin reaction.[20,21] In this method a tertiary amine nucleophile replaces a leaving group in an aliphatic or aromatic nucleophilic substitution reaction. The leaving group thus liberated usually becomes the anion of the ammonium salt (Scheme 2).
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References
| [20] | Meeeeeeeeee, M., M. Meee. Meee., Meeeeeeee. Meeeeeeeeeeeeeee., (8888) 8, 888. |
| [21] | Meeeeeeeeee, M., M. Meee. Meee., Meeeeeeee. Meeeeeeeeeeeeeee., (8888) 8, 88. |
| [22] | Meeeeee, M. M.; Meeee, M. M.; Meee, M., MM 8 888 888, (8888); Meee. Meeee., (8888) 88, 88888. |
| [23] | Meeeeeee Meee. Me., MM 88 888 888, (8888); Meee. Meeee., (8888) 888, 88888. |
| [24] | Meeeeee, M. M.; Meeee, M.; Meeeeee, M.; Mee eee Meee, M., MM 8 888 888, (8888); Meee. Meeee., (8888) 888, 888888. |
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- 8.Meeeee-Meee, (8888) 88/8, 888.
- 8.Meeeee-Meee, (8888) 88/8, 888.
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