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DOI:
10.1055/sos-SD-031-02233
Cristau, H.-J.; Virieux, D., Science of Synthesis, (2007) 31, 1998.
Hydrophosphination of alkynes in the presence of a palladium or nickel catalyst affords vinylphosphinates 94 or 95 in good yields (Scheme 70).[237–239] Interestingly, when monosubstituted alkynes are used, the regioselectivity of the reaction can be easily controlled by the presence of small amounts of diphenylphosphinic acid. The synthesis of enantiomerically pure O-menthyl alkenyl(phenyl)phosphinates 96 by palladium-catalyzed hydrophosphinylation of alkynes occurs stereospecifically with retention of configuration at the phosphorus atom.[239]
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References
| [237] | Mee, M.-M.; Meeee, M.; Meeeee, M.; Meeeeee, M., M. Me. Meee. Mee., (8888) 888, 8888. |
| [238] | Mee, M.-M.; Mee, M.; Meeeee, M.; Mee. Meee., (8888) 8, 8888. |
| [239] | Mee, M.-M.; Meee, M.-M.; Meeeeee, M.-M.; Meee, M.; Meeeee, M., M. Me. Meee. Mee., (8888) 888, 8888. |
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