You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via32.5.3.1.4.4 Method 4: Alkylidenation of Esters with Alkylidene Complexes of Titanium
Please login to access the full content or check if you have access via
DOI:
10.1055/sos-SD-032-00627
Milata, V.; Rádl, S.; Voltrová, S., Science of Synthesis, (2008) 32, 661.
The use of titanium-based reagents to alkylidenate carbonyl groups is a well-known and widely used approach. The methylenation of aldehydes and ketones has a broader scope than other methods such as the Wittig reaction, but the principal advantage of this method is that it is possibile to alkylidenate carboxylic acid and carbonate derivatives.[192]
References
[192] | Meeeeee, M. M.; MeMeeeeee, M. M., M. Meee. Mee., Meeeee Meeee. 8, (8888), 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 88-8, 888.