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33.4.19.1.2.1 Method 1: Reduction/Elimination of a Lactam

DOI: 10.1055/sos-SD-033-00680

Quirion, J.-C.Science of Synthesis, (200733643.

Reduction of a lactam carbonyl followed by dehydration provides a conceptually simple route to enecarbamates (Scheme 27), described for the synthesis of five-membered ring derivatives in Section 33.4.17.1.2.1. The same methods have been applied to the preparation of various substituted 1,2,3,4-tetrahydropyridine carbamates.[‌33‌‌39‌]

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