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33.5.2 Product Subclass 2: Alk-1-enylphosphinic Acids and Derivatives

DOI: 10.1055/sos-SD-033-00773

Gaumont, A. C.; Gulea, M.Science of Synthesis, (200733695.

General Introduction

Monosubstituted phosphinic acids and their esters are important intermediates in the syntheses of many biologically active compounds.[‌1‌] Fewer general methods are available for the synthesis of the alk-1-enylphosphinates than is the case for the corresponding alk-1-enylphosphonates, but many of the reactions that can be applied in the synthesis of phosphonates can also be applied in the synthesis of phosphinates.

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