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35.2.5.2.5 Method 5: Hydrobromination of Epoxides Using Tin(II) Bromide

DOI: 10.1055/sos-SD-035-00442

Rück-Braun, K.; Freysoldt, T.Science of Synthesis, (200735510.

Very few examples are known for the formation of bromo alcohols 31 from epoxides 30 using tin(II) bromide.[‌7‌,‌43‌] In the examples shown in Scheme 13, the reaction conditions are mild and a variety of solvents can be used, but the reaction gives only moderate yields. No detailed experimental procedures are described in the literature.

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References


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