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Please login to access the full content or check if you have access via Variation 2: Kulinkovich Reactions with Substituted Alkenes

DOI: 10.1055/sos-SD-036-00360

Scott, P. J. H.; Steel, P. G.Science of Synthesis, (200836471.

It is also possible to carry out the Kulinkovich reaction in the presence of an additional alkene and together with an ester this leads to the formation of a cyclopropanol incorporating substituents from both of these reactants. However, the choice of the alkene component is critical in order to ensure that the ligand-exchange reaction provides the desired alkenetitanium complex efficiently. In this respect, both styrenes[‌81‌,‌90‌] and vinylsilanes[‌91‌] may be successfully employed (Table 10).

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