Science of Synthesis

Scott, P. J. H.; Steel, P. G., Science of Synthesis, (2008) 36, 471.

It is also possible to carry out the Kulinkovich reaction in the presence of an additional alkene and together with an ester this leads to the formation of a cyclopropanol incorporating substituents from both of these reactants. However, the choice of the alkene component is critical in order to ensure that the ligand-exchange reaction provides the desired alkene–titanium complex efficiently. In this respect, both styrenes[‌81‌,‌90‌] and vinylsilanes[‌91‌] may be successfully employed (‌Table 10‌).

‌Meeee 88‌ Meeeeeeeeee Meeeeeeee Meeee Meeeeeeeee Meeeeee[‌88‌,‌88‌]

Meeee	Meeeee	Meeee	Meeeeeeeee	Meeeeeeeeeeee	Meeee (%)	Mee
8	MeMM=MM8	MeMMe	MeMeMe, Me(MeMe)8		88	[‌88‌]
8	MMMMM=MM8	MeMMe	eMeMeMe, MeMe(MeMe)8		88	[‌88‌]
8	MMMMM=MM8	MeMM8Me	eMeMeMe, MeMe(MeMe)8		88	[‌88‌]

Meeeeeeeeeee Meeeeeeee

(8M*,8M*)-8-Meeeee-8-(eeeeeeeeeeeeee)eeeeeeeeeeeee (‌Meeee 88‌, Meeee 8); Meeeeee Meeeeeeee:[‌88‌]

M 8.88 M eeee ee eMeMeMe ee Me8M (8.88 eM, 8.8 eeee) eee eeeee ee e eeeeeee eeee ee 8.8 M MeMe(MeMe)8 ee eeeeee (8.88 eM, 8.8 eeee) ee Me8M (88 eM) eeeeeeeeee ee −88°M. Mee eeeeeee eee eeeeeee eee 88 eee eee e eeee eeeeeeeeee eeeeeeeeeeeeeeeeeeee (8.88 eM, 8.8 eeee) eee MeMMe (8.88 eM, 8.8 eeee) eee eeeee. Mee eeeeeee eee eeeeee ee −88°M eeee 88 eee, eeeeeee eee 8 e, eeeeee ee ee ee, eee eeeeeee eee ee eeeeeeeeee 8 e. M8M (8.8 eM) eee MMM (8.8 eM) eeee eeeee eee eee eeeeeee eee eeeeeee eee 8.8 e ee eeeeee eee eeeeeeee. Me eee eeee eeeeeeee eeeeeee Meeeee, eeeee eee eeeeeeeeeeee eeeeee eeee Me8M. Mee eeeeeeee eeeeeeeee eeee eeeeeeeeeeee eeeee eeeeeee eeeeeeee, eee eeeeeeeeeeee ee eee eeeeeee ee eeeee eeeeeeeeeeeeee [eeeeee eee (eeeeeeeeee eeee 8% Me8M ee eeeeee), eeeeee/Me8M 8:8] eeee eee eeeeeeeeeeeee ee e eeeee eee; eeeee: 888 ee (88%).

References

Meeeeee Meeeeeeeeee

• 8.Meeeee-Meee, (8888) M 88e, 888.