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DOI:
10.1055/sos-SD-036-00589
Nativi, C.; Roelens, S., Science of Synthesis, (2008) 36, 757.
1,2-Diols play an important role in biological systems. They have also found frequent use as starting materials for the enantio- or diastereoselective syntheses of natural products and drugs, as chiral auxiliaries, and as transition-metal ligands for asymmetric synthesis and catalysis.[3,4] A number of powerful asymmetric reactions for the synthesis of syn-1,2-diols have emerged; however, the diastereoselective syntheses of anti-1,2-diols still remain less common than those of the syn-analogues.
References
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- 8.Meeeee-Meee, (8888) 8/8e, 888.