You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via36.7.2 Product Subclass 2: 1,3-Diols
Please login to access the full content or check if you have access via
DOI:
10.1055/sos-SD-036-00589
Nativi, C.; Roelens, S., Science of Synthesis, (2008) 36, 774.
Many polyketide-derived natural products contain syn- or anti-1,3-diol fragments. Since polyketides constitute a class of compounds among the most biologically active known to date, a great deal of attention has been focused on their stereoselective synthesis. The development of different methods for the stereoselective preparation of 1,3-diols is of paramount importance as, often, even small structural variations result in a lower yield or selectivity than expected according to a known general method. Several reviews are available concerning 1,3 diols and related compounds.[88–92]
References
[88] | Meeee, M.; Meeeee, M., Meeeeeeee, (8888), 888. |
[89] | Meeeeee, M. M.; Meeee, M. M.; Me, M. M., Meee. Mee., (8888) 88, 8888. |
[90] | Meeeeeeee, M., Meeee. Meee., (8888) 888, 8888; Meeee. Meee. Mee. Me., (8888) 88, 8888. |
[91] | Meeeeeee, M. M.; Meeeeeee, M., Meee. Mee., (8888) 88, 8888. |
[92] | Meee, M. M.; Meeeeee, M.; Müeeee, M., Meeeeeeee, (8888), 888. |