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DOI: 10.1055/sos-SD-037-00384

Inoue, M.; Yamashita, S.Science of Synthesis, (200837605.

This method incorporates etherification from cyclic acetals, which is one of the most general and powerful methods for the synthesis of oxacycloalkanes. It has been demonstrated to be applicable to highly complex architectures and is categorized into three variations: reduction of hydroxy ketones or hemiacetals to ethers (Section, reduction of O,O- or O,S-acetals to ethers (Section, and alkylation of cyclic acetal derivatives (Section