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Please login or sign up for a free trial to access the full content. Variation 1: Addition of Dialkyl Phosphites to Alkenes, Allenes, and Alkynes

DOI: 10.1055/sos-SD-042-00767

Drabowicz, J.; Kiełbasiński, P.; Łyżwa, P.; Mikołajczyk, M.; Zając, A.Science of Synthesis, (200942730.

Earlier examples of this reaction are described in HoubenWeyl, Vol. 12/1, pp 463475 and Vol. E 2, pp 353355 and elsewhere.[‌204‌] This reaction can be catalyzed by palladium to give, for example, alkylphosphonates 57 (Scheme 97).[‌208‌,‌209‌] It can also be carried out with alkynes to give bisphosphonates (e.g., 58, Scheme 98).[‌210‌]

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M8 M8 Meeeeeeeee Meeee (M/M) Meeee (%) ee 88 Mee
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M8 Me8 Meeee (%) Mee
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Me 8-eeeeeee 88 [‌888‌]
Me 8-M8MM8M8 88 [‌888‌]
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