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DOI:
10.1055/sos-SD-043-00002
Hirsch, A.; Vostrowsky, O., Science of Synthesis, (2008) 43, 38.
Acetylides with transition metal—carbon σ-bonds are suited for C—C coupling reactions, and as long ago as 1869 Glaser observed that the smooth oxidative dimerization of copper(I) phenylacetylide (2), prepared from phenylacetylene (1), takes place in the presence of air and gives 1,4-diphenylbuta-1,3-diyne (3) (Scheme 1).[50] This discovery has since made metal-catalyzed oxidative alkyne dimerization one of the most relevant and attractive C—C bond-forming transformations available to modern chemists.
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References
| [50] | Meeeee, M., Mee. Meeee. Meee. Mee., (8888) 8, 888. |
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- 8.Meeeee-Meee, (8888) 8/8e, 888.
- 8.Meeeee-Meee, (8888) 8/8e, 888.
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