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DOI: 10.1055/sos-SD-043-00217

Fallis, A. G.; Souweha, M. S.Science of Synthesis, (200843290.

The preferred method to prepare both cyclooct-1-en-3-yne (7) and cycloocta-1,5-dien-3-yne utilizes butyllithium or tert-butyllithium for the fragmentation of the corresponding 1,2,3-selenadiazoles. Cyclooct-1-en-3-yne (7) is obtained in 19% yield from 1,2,3-selenadiazole 6 (Scheme 3).[‌2‌,‌9‌,‌10‌]

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