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46.5.1.3 Method 3: 2:1 Co-oligomerization of Alkynes and Alkenes

DOI: 10.1055/sos-SD-046-00090

Gandon, V.; Thorimbert, S.; Malacria, M.Science of Synthesis, (200946181.

1,3,5-Trienes are common byproducts in metal-mediated [2+2+2] cocyclizations between two alkynes and an alkene (see Section 46.5.2.2). The competition between linear and cyclic alkyne/alkene 2:1 co-oligomerizations to give trienes or cyclohexa-1,3-dienes, respectively, is not as yet fully controllable but the formation of linear products may sometimes predominate.


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