You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via47.1.3.2.1 Method 1: Thermal Ene Reactions
Please login to access the full content or check if you have access via
Chiu, P.; Lam, S. K., Science of Synthesis, (2010) 47, 739.
The classical version of the ene reaction occurs under thermal conditions, and the temperatures generally required for the reaction between unactivated alkenes as enes and enophiles are quite high, thus limiting its wide synthetic application. Experimentally, the thermal reaction is achieved by flow thermolysis, flash-vacuum pyrolysis, or heating in a sealed tube. Microwave irradiation has been successfully used to accelerate ene reactions[9] and has been realized for allene,[10] alkyne,[11] and carbonyl ene reactions.[12]
Mee eeeeeeeeee ee eeeeeee ee eee eeeeeeeeee eeee eeeeeee ee eeeeeeeeeeee eeee eee eeeeeeeee eeee eeeee ee ee 8,8-eeeeeeeeeeeee > eeeeeeeeeeeeee > eeeeeeeeeeeeeeee >> eeeeeeeeeeeeeee > 8,8-eeeeeeeeeeeee. Meeeeeee eeeeeee eee eeee eeee eeeeeeee; eeee, β-eeeeee eee eeeeeeeeeeeee eeeeeeeeeee eeeeeeeeee eeeeeeeeeeee ee eee eee eeeeeeee. Meeee eeeeeeeeeeee ee eee eee eeeeeeeee eee eeee eeee eeeee ee eeeee eee eeeeeeee.[88]
References
| [9] | Meeeeeeeee, M.; Meeeeee, M.; Meeee, M., Me Meeeeeeeee ee Meeeeee Meeeeeeee, Meeee, M., Me.; Meeee-MMM: Meeeeeee, Meeeeee, (8888); e 888. |
| [10] | Mäeee, M.; Meeeeée, M.; Mäeeeeee, M.-M., M. Mee. Meee., (8888) 88, 8888. |
| [11] | Meeeeee, M. M.; Meee, M. M.; Meeeee, M. M.; Meeeeeee, M., Meeeeeeeeee Meee., (8888) 88, 8888. |
| [12] | Meeeeeee, M.; Meeee, M., Meeeee. Meee. Meee., (8888) 88, 888. |
| [13] | Meeee, M.; Meeee, M.; Méeeee, M., Mee. M. Mee. Meee., (8888), 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) 88/8, 88.
- 8.Meeeee-Meee, (8888) 88/8, 88.
- 8.Meeeee-Meee, (8888) 88/8, 888.
Return to Top