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47.1.4.4.2 Variation 2: Dehydration of Alcohols Using Lewis Acids and Heterogeneous Catalysts

DOI: 10.1055/sos-SD-047-00322

Kostikov, R. R.; Khlebnikov, A. F.; Sokolov, V. V.Science of Synthesis, (201047803.

Some heterogeneous reactions using almost stoichiometric amounts of dehydrating agents, such as anhydrous copper(II) sulfate or trifluoromethanesulfonate,[‌123‌] iron(III) chloride on silica gel,[‌124‌] or the boron trifluoridediethyl ether complex,[‌125‌] also produce alkenes.

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Meeee 88 Meeeeeeeeee ee Meeeeeee Meeeeeeee ee Meeeeeeee Meeeee(MM) Meeeeee[‌888‌]

Meeeeee Meeeeeeeee Meeeeee(e) Meeee (%) Mee
888°M, 88Meee, 8.8e 88 [‌888‌]
888°M, 8.8Meee, 8e 88 [‌888‌]
888°M, 888Meee, 8.8e 88 + 8 [‌888‌]
888°M, 888Meee, 8e 88 + 88 [‌888‌]
888°M, 888Meee, 88e 88 [‌888‌]
888°M, 888Meee, 8e 88 + 88 [‌888‌]
888°M, 888Meee, 8e 88 [‌888‌]
888°M, 888Meee, 8.8e 88 [‌888‌]

Meeeee(MM) eeeeeeeeeeeeeeeeeeeeeeeee eee eeee eeeeeeee ee e eeeeeeeeeee eeeeeee eee e eeeeeee ee eeeeeeee (Meeee 88).[‌888‌] Mee eeeeeeeeeee eeee eeee eeeeee eeeeeeee ee eeee eeeeeeeee eeee eeee 88% eeeeeeee eeee[‌8‌] ee eeeeeeeeee eeeeeeeeeeeeeeee[‌888‌] eee eeeee-8-ee, 8-eeeeeeeeeeee-8-ee, eee eeeeeeeee-8-ee.

Meeee 88 Meeeeeeeeee ee Meeeeeee eeee Meeeee(MM) Meeeeeeeeeeeeeeeeeeeeeeee[‌888‌]

Meeeeeee Meeeeeee Meeeeee(e) Meeee (%) Mee
88 + 8 [‌888‌]
88 + 88 [‌888‌]
88 + 8 [‌888‌]
88 [‌888‌]
88 + 8 [‌888‌]
88 [‌888‌]
88 + 8 [‌888‌]
8888 [‌888‌]

Meee(MMM) eeeeeeee eeeeeeee ee eeeeeeeeeeeeee-eeeee eeeeee eee ee eeeeeeeee eee eeeee, eeee-eeeeeeee, eee eeeeeeeee eeeeeeeeeee ee eeeeeeee. Mee eeeeeee, eeeeeeeeeeeeee 8,8-eeeeeeeeeeeeeeeeeeeee eeee 8,8-eeeeeeeeeeeeeeeeeee ee >88% eeeee.[‌888‌]

M-Meeeeeeeeeeeeee eeee ee e eeeeeeeeeee eeeeeeee eee eeeeeeee eeeeeeee, eeeeee eee eeeeeeeeeeeee eeeeeee (e.e., 88 eee 88) ee eeeeeeeee eeeeee; ee eee ee eeeeeeee eeeeee eeeeeeeeeeeeee (Meeee 88).[‌888‌] Meee eeeeeeeee eee eee eeeeeeeeeee ee eeeeeeee eeee eeee eeee ee ee eeeeeeeeee eeeee eee ee eee eeeeeeeeee eee eeeeeee eeeeeee, eee eeeee ee e eeee eee eeeeeeeeeeeeeee eeeeeeee eeeeeeeee eeee eeee eeeee eeee eeeeeeeeee.

Meeee 88 Meeeeeeeeeeeeee-Meeeeeeee Meeeeeeeeee ee Meeeeeee ee Meeeeee[‌888‌]

Meeeeeee Meeeeeee Meeeeee(e) Meeee (%) Mee
88 + 88 [‌888‌]
88 + 88 [‌888‌]
88 + 88 [‌888‌]
88 + 88 [‌888‌]
88 [‌888‌]
88 [‌888‌]
88 [‌888‌]

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Meeeeeeeeee ee eeeeee-8-ee eee 8,8-eeeeeeeeeeeee-8-ee eeee eeeeeee ee 888°M eeeee eeeeeeee ee eee-8-eeee (8888%) eee eee-8-eeee (8888%).[‌888‌] Meeeeee-8-ee eee ee eeeeeeeeee ee eeee eeeeeeeeeeee ee eeeeeeee eeeeee (Me8M8, Me8M8, MeM8, MM8) ee eeee eeeee-8-eee.[‌888‌]

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Meeeeeeeeeeeeeeeeee(MMM) eeee eeeeeeeee eee eeeeeeeeeee ee eeeeeeee ee eeeee eeeeeee (Meeee 88).[‌888‌] Mee eeeeeeeeeee ee eeeeeeeee eeeeeeee eee eeeeeee eee ee eee eeee eeeeeee. Meeeeeee eeeeeeee eee eeeeee eeeeeeeeee ee eeeeeee ee eeeeeee eeeeeeee.

Meeee 88 Meeeeeeeeeeeeeeeeee(MMM) Meeeeeeee Meeeeeeeeee ee Meeeeeee ee Meeeeee[‌888‌]

Meeeeeee Meeeeeee Meeeeee Meeee (%) Mee
eeeee-8-eee eee-8-eee 88e [‌888‌]
eeeeeee-8-eee eeeee-8-eee 88e [‌888‌]
eeeeeeeeeeeee eeeeeeeeeee 88e [‌888‌]
eeeeeeeeeeeeeeeeeee eeeeeeeeeeeeeeeeeeee 88e [‌888‌]
8-eeeeeeeeeeeee eeeeeee 888 [‌888‌]
8-eeeeeeeeeeee-8-ee 8-eeeeeeeeee-8-eee 888 [‌888‌]
8-eeeeeeeeeeee-8-ee 8-eeeeeeeeee-8-eee 88 [‌888‌]
8-eeeeee-8-eeeeeeeeeeee-8-ee 8-eeeeee-8-eeeeeeeeee-8-eee 88 [‌888‌]

e Meeeeee eeee ee eeeeeee.

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Mee(eeeeeeeeeeeeeee)eeeeeeeeeeeeeee(MM) eeeeeeeee eee eeeeeeeeeee ee eeeeeeee eeeeeeee ee eeeeeee eeee ee 88 eee 88 ee eeee eeeeee (Meeee 88).[‌888‌] Meeeeee, eeee eeeeeeee eeeeeeee eeee eee eeeeeeeeeeeeeeee. Meeeeeeee eeeeeeee ee eee eeeeeee eeeeeeeeeee eeeee eeeee eeeeeeeeee.

Meeee 88 Meeeeeeeee-Meeeeeeee Meeeeeeeeee ee Meeeeeee Meeeeeee ee Meeeeee[‌888‌]

Meeeeeee Meeeeeee Meeeeee(e) Meeee (%) Mee
88 + 88 [‌888‌]
88 + 88 [‌888‌]
88 + 88 [‌888‌]
88 + 88 [‌888‌]
88 [‌888‌]

Meeeeeeeeeee Meeeeeeee

8-Meeeeeeeeeee-8-eee (88) eee 8-Meeeeeeeeeee-8-eee (88); Meeeeee Meeeeeeee Meeee M-Meeeeeeeeeeeeee:[‌888‌]

M-Meeeeeeeeeeeeee eee eeeeeeee eeee eeeeeeeeee eeeeeeeeeeeeeee M. Me e eeee ee 8-eeeeeeeeeeeeee-8-ee (888ee, 8eeee) ee eee-eeee eeeee eeeeeee (88eM) eee eeeee eeeeee-eeeee M-eeeeeeeeeeeeeee (888ee). Mee eeeeeee eee eeeeee eeeee eeeeee eeeee eeeee, eeee eeeeeeee. Meeee 8e, eee eeeeeee eee eeeeee ee ee eee eeeeeeee, eee eeee ee eee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeee eee eeeeeee eeee Me8M (88eM), eeeeee eeee eee. MeMe eeee eee M8M, eee eeeee (Me8MM8). Meeee eeeeeeeeeee ee eee eeeeeee, e eeeee, eeeeeeeee eee eeeeeeeeee 88 eee 88 ee e eeeee ee 8:8 eee eeeeeeee; eeeee: 888ee (88%).

8-Meeeeeeeeeee-8-eee (88) eee 8-Meeeeeeeeeee-8-eee (88); Meeeeee Meeeeeeee Meeee Mee(eeeeeeeeeeeeeee)eeeeeeeeeeeeeee(MM):[‌888‌]

Me e eeee ee 8-eeeeeeeeeeeeee-8-ee (888ee, 8eeee) ee eeeee, eee-eeee eeeeeee (88eM) eee eeeee MeM8(eeee)8 (88ee, 8.8eeee). Mee eeeeeee eee eeeeee eeeee eeeeee eeeee eeeee, eeee eeeeeeee, eeeeeeeee eee eeeeee-eeeeee eeeeeeeeee eeeeee eeee. Meeee 8e, eee eeeeeee eee eeeeee ee ee, eee eeee ee eee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeee eee eeeeeee eeee Me8M (88eM), eeeeee eeee MeMMM8 eeee, M8M, eee eee. MeMe eeee, eee eeee eeeee (Me8MM8). Meeee eeeeeeeeeee, e eeeee, eeeeeeeee eee eeeeeeeeee 88 eee 88 ee e eeeee ee 8:8 eee eeeeeeee; eeeee: 888ee (88%).

References