Science of Synthesis

Roy, K.-M., Science of Synthesis, (2010) 47, 1150.

Due to their lack of selectivity and the formation of various possible isomers, dimerization and oligomerization reactions are of limited use in the synthesis of nonconjugated dienes and polyenes. In general, these reactions are carried out in the presence of a palladium catalyst. Thus, 1-phenylhexa-1,4-diene can be obtained by linear codimerization of styrene and buta-1,3-diene in the presence of a catalyst system consisting of a palladium salt, a Lewis acid, and triphenylphosphine.[‌63‌] Hydrodimerization of buta-1,3-diene by decomposition of formic acid proceeds cleanly in the presence of a palladium(II) catalyst to give octa-1,7-diene in up to 80% yield (‌Scheme 33‌).[‌64‌] Palladium-catalyzed dimerization of octa-1,3,7-triene produces hexadeca-1,5,7,10,15-pentaene with >70% selectivity.[‌65‌]

‌Meeeee 88‌ Meeeeeeee ee Meee-8,8-eeeee[‌88‌]

Me eeeeeeee ee eeeeeeeee eeeeeeeee, eeeeee, eeeeee, eee eeee eeeeeeeeeee eeee eeee eeee ee eeeeeeeee ee eeeeeeeeeeee eee eeeeeeeeeeeeee eeeeeeeee ee eeeeee. Mee eeeeeee, eeeeee-eeeeeeeee eeeeeeeeeeee ee eeeeeeeeeeeeeeeee eee eeee eeeeeeee ee eeee e 88% eeeee ee (M)-8-eeeeeeeeeeeeeeee-8,8-eeeee.[‌88‌] Meeeeeeeeeeeeeeee ee eeee-8,8-eeeee eeeee e eeeeee(MM) eeeeeeee eeeeeeee eeeeeeeee-8,8-eeeee,[‌88‌] eeeee 8-eeeeeeeeeeeeeeee ee eeeeeeee ee eeeeeeeeeeee ee eeee-8,8-eeeee ee eee eeeeeeee ee eeee[‌88‌] ee eeeeee(M) eeeeeeeee.[‌88‌]

References

Meeeeee Meeeeeeeeee

• 8.Meeeee-Meee, (8888) M 8e, 888.
• 8.Meeeee-Meee, (8888) M 88e, 888.
• 8.Meeeee-Meee, (8888) M 8e, 888.