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1.4.5.2.2.16.3 Variation 3: Hydrovinylation of Alkenes

DOI: 10.1055/sos-SD-101-00001

Amatore, M.; Aubert, C.; Malacria, M.; Petit, M.Science of Synthesis Knowledge Updates, (2012394.

Among the alkene dimerization reactions, the hydrovinylation reaction, resulting in the addition of a vinyl group and hydrogen across a double bond, offers great potential for practical synthetic applications. However, well-defined procedures for these reactions need to be developed in order to solve scope and selectivity issues. On the other hand, since some branched products presenting a stereogenic center can be obtained, enantioselective versions of this reaction have been described.

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