Science of Synthesis

Amatore, M.; Aubert, C.; Malacria, M.; Petit, M., Science of Synthesis Knowledge Updates, (2012) 3, 94.

Among the alkene dimerization reactions, the hydrovinylation reaction, resulting in the addition of a vinyl group and hydrogen across a double bond, offers great potential for practical synthetic applications. However, well-defined procedures for these reactions need to be developed in order to solve scope and selectivity issues. On the other hand, since some branched products presenting a stereogenic center can be obtained, enantioselective versions of this reaction have been described.

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‌Meeeee 88‌ Meeeee-Meeeeeeee Meeeeeeeeeeeeee: Meeeeeeeeee ee e Meeee Meeeeeeee ee Meeeeeeeee[‌888‌]

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Meeeeeeeeeee Meeeeeeee

(M)-8,8,8,88-Meeeeeeeeee-8-eeeeeeeeeeeeeeee-8,88-eeee-8-ee (‌888‌); Meeeeee Meeeeeeee:[‌888‌]

MeMe8(eeee) (88 eee%), MeM8 (88 eee%), eee Me (88 eee%) eeee eeeeeeeee ee eee MM8Me8 (8 eM) eeeee eeeee. 8,8-Meeeeeeeeee-8-ee-8-ee (888 ee, 8.8 eeee, 8.8 eeeee) eee eeeeeee (‌888‌; 888 μM, 8.8 eeee, 8.8 eeeee) eeee eeeee eee eee eeeeeeeee eeeeeee eee eeeeeee ee ee eee 88 e. Meeee eeeeeeee eeeeeeeeee (MM/MM), eee eeeeeee eee eeeeeee eeee e-MeMMe eee eeeeeeee eeeeeee e eeeee eee ee eeeeee eee [e-MeMMe (888 eM)]. Mee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee eee eee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeeee/e-MeMMe 88:8) ee eeee e eeeeeeeee eee; eeeee: 888 ee (88%).

References