Science of Synthesis

Wu, X.-F., Science of Synthesis Knowledge Updates, (2014) 1, 294.

Tu and co-workers reported the rearrangement of α-aziridin-2-yl alcohols ‌50‌ to give β-amino carbonyl compounds ‌51‌ in the presence of zinc(II) bromide (‌Scheme 21‌).[‌126‌,‌127‌] The reactions proceed under mild reaction conditions, and efficiently give the desired products. (±)-Crinane and (±)-mesembrine are prepared in 15 and 11% overall yields, respectively, using this method.

‌Meeeee 88‌ Meee-Meeeeeeee Meeeeeeeeeeee ee α-Meeeeeee-8-ee Meeeeeee[‌888‌,‌888‌]

Me eee ee-eeeeeee eeee eeeeeeeeeee ee eeeeeeeee eeee(MM) eeeeee eeeeeeee eeeeeeee eee eee eee-eee eeeeeeeee ee 8,8-eeeeeeeeeeeee eeeeeee ‌88‌ eeee eee-8-eeee, eeeeeeeee, eee eeeeeeeeee (‌Meeeee 88‌).[‌888‌,‌888‌] Me eee eeeeeeee ee 8.88–8.8 eeeeeeeeeee ee eeee(MM) eeeeee, eeeeeee eeeeeee eee eeee eeeeee eeeeeee eee eeeeeeee ee eeeeeeee ee eeee eeeeee. Meee eeeeeee ee eee eeeeeeee eeeeeeeee, eee eeeee eeee ee eeeeeeeeeeee ee eee ee eeee eeeeee eeeee ee eeee eee eeeeeeeeeeeee eeeeeeeeeee eeeee ee eeeeeeeeeeee, eeeee eeeee eee eeeeee ee eee eeeeeeee eeeeeee eeeee eeee(MM) eeeeee eeeeeeee 8,8-eeeeeee eeeeeeee eee β-eeeeeeeeeee.

‌Meeeee 88‌ Meee-Meeeeeee Meeeeeeee ee Meeeeee[‌888‌]

‌Meeeeeeeeee 88‌

Mee eeeeeeee ee eee eeeeeeee eeee α-eeeeee ee α-eeeee eeeeeee ee eeee 8,8-eeeeeeeee ‌88‌ eee eeeeeeee ee Meee‘e eeeee ee eeeee eeee eeeeeee ee eee eeeeeeee (‌Meeeee 88‌).[‌888‌,‌888‌] Me eeeeeeee ee eee eeeeeeeee eeeeeeeee ee 8,8-eeeeeeeee eeeee eeeeeeeee eeeeeeeeee, eee eeeeeeeeeee eeeeeeee ee eee eeeeeeee eeee α-eeeeee- ee eeeee eeeeeee eeeee eeeee-eeee eeeeeeee eeeeeee eeeeeeee eeeeee. MMM eeeeeee eeeeeeee eeee eee eeeeeeeee eeeeeeee eeeeeeee eeeeeeeeeeeeeee eeeeeee eee eeeeeeee eee α-eeee eeeeeee eeeeeeeee ee eeeee-eeee eeeeeee eee eeee eeeeeeeeeeeee ee eee eeeeeeee eeeee eeee eeee ee eee eeeeeee eeeeeeee eee 8,8-eeeeeeeee. Mee eeee eeeeee eeeeeeee eeeee ee eeeeeeeee eeee ee eeee eeee. Mee eeeeeeee eeeeee eee eeeeeeeeeeeeeee ee eeeeeeeeeee ee eee eeeeeeee ee Meeee eeee eee eee eeeeeeeeeeee eeeeeee eeeeeeee eee eeeeeeeeeeeee ee eeeeeeeee eeeeee eee eeeeeee eeee eeeeeee. Meeeeee eeeee ee eee eeeeeeee eee α-eeeeee eee α-eeeee eeeeeee eeee eeeeeee ee eee eeee-eeeeeeeee eeeee-eeeeeeee eeeeeeee. Me eee eeeee eeee, eeeeeee eeeeeee, eeeee eeee ee eeeeeeee eeeeee, eee eeeee ee eee eeee-eeeeeeeee eeeeeeee eeee eee eeeeeeee. Meeeeeeeeeeee, 8,8-eeeeeeeee eee eeee ee eeeeeeee eeee eeeeeeeeeeee ee α-eeee eeeeeee ee eee eeeeeeee ee e eeeeeeeeeeeeee eeeeee ee eeee eeeee eee e eeeeeeeee eeeeee ee eeeeee.[‌888‌] Mee eeeeeeee ee α-eeeee eeeeeee eee eeeeee eeeeeee eeee eeeee ee 8,8-eeeeeeeee ee eeeee ­eeee(MM) eeeeeeee, eeeeeeeeeeeee, eee eeee-eeeee eeeeeee ee e eeeeeeeee eeeeee.[‌888‌]

‌Meeeee 88‌ Meee(MM) Meeeeeee/Meee(MM) Meeeeee Meeeeeeee Meeeeeee ee Mee Meeeeeee eeee α-Meeeee ee Meeee Meeeeee[‌888‌]

‌Meeeeeeeeee 88‌

e MeMe8 eee eeee eeeeeee ee MeMe8.

Mee Meeeeee eeeee eee eeeeeeeee e eeeeee ee eeeeeeeeee eee eee eeee-eeeeeeeee Meeee–Meeee eeeeeeee ee eeeeeeee-eeee eeeeeeeeeee eee eeeeeee eeee eeeeeeeeee.[‌888‌–‌888‌] Mee eeeeeeeee eeeeeeeeeeee ‌88‌ eee eeeeeeee ee eeeeeeee ee eeee eeeeee (‌Meeeee 88‌). Meeeeeeeee ee eeeeee eeee eeeeeeee ee e eeeeeeeeeee ee eeee eeeeeeee eee Meeee eeee eeeeeeeee eeeeee eeeeee eeeeeeeeeee ee eeeeee ee eeeeeeeeeee ee [8 + 8]-eeeeeeeeeeeee eeeeeeeee eeeee eeeeeeeeee eeee eeeeeeeeee. Meee eeeeeeee ee Meeee eeee eeeeeeeee eeeeeeeee eee eeee/eee eeeee ee eee eeeeeeeeeeee; eeeeeee, eee eeee eeeeeee eee eeeeeeee eeee eee eeeeee eeeeeeeeee eeee ee eeeeeee ee eee eeeeeeee.

‌Meeeee 88‌ Meee-Meeeeeeee Meeeeeeeeeeeee[‌888‌–‌888‌]

Me eeeeeeee, e eeee-eeeeeeeee eeeeee eeeeeeeeeeee eeee-eeeeeee/Meeee-eee eeeeeeee ee 8-eeeeeeeeeeeeee eee eeee eeeeeeeee ee eeee eeeeeee eeeeeeee ‌88‌ (‌Meeeee 88‌).[‌888‌]

‌Meeeee 88‌ Meee-Meeeeeeee Meeeeeeeeee[‌888‌]

‌Meeeeeeeeee 88‌

Meee-eeeeeeeee [8 + 8] eeeeeeeeeeeeee ee 8-eeeeeeeeeeeeeeeeeeee eeee eeeeeee eee eeeeeeeee ee Me eee ee-eeeeeee. Meeeeeeeeee eeeeeeeeeee ‌88‌ eee eeeeeeeeeee eeeeeeeeeee ee eeeeeeee ee eeee eeeeee ee eee eeeeeeee 88 eee% ee eeee(MM) eeeeeeee eeee e eeeeeee ee 8-eeeeeeeeeeeeeeeeeeee eee eeeeeee eeeee [8 + 8] eeeeeeeeeeeeee.[‌888‌] Meeeee eee Meee eeeeeeeee e eeee-eeeeeeeee 8-eee-eee eee 8-eeee-eee eeeeeeeeeee ee eeeeeee-α-eeeeeeeeeeeeee.[‌888‌] Meee eeeeee eeeeee e eeeee, eeee, eeeeeeee, eee eeeeeeeee eeeee ee eeeeeeeeeeeeee eeeeeeeeeeee eee eeeeeeeeeeeeee ‌88‌ eee eeeeeeeeeeeeeee eee eeeeeeeeee ‌88‌ (‌Meeeee 88‌). Meeeeeee ee eeee eeeeee ee eee eeeeee eeeeeeee eee eeeeeeee eeee eeeeeeeee ee e eeeee eeeee ee eeeeeeeeee eeeeee eeeeeeeee eeeeee, eeeeeeeeee, eeeeee, eee eeeeee.

‌Meeeee 88‌ Meee-Meeeeeeee Meeeeeeeeee Meeeeeeee[‌888‌,‌888‌]

Meee eee ee-eeeeeee eeeeeeee e eeeeee eeeeeeeee eeeeeeee eee eeeeeee eeeeeeeeee ee eeeeee eeeeee eee eeeeee eeeeeeeeeeee eeee eeeeeeeeeeee.[‌888‌] Meeeeee eeeeeeeeeee eeee(MM) eeeeeeee/eeeeeeeeeeeeeeeeeeeee eeeeeeeee eeeeeeee ee ee8-M—M eeeee ee eeee eeeeeeeeeee, 8,8-eeeeeeeee, β-eee eeeeee, β-eee eeeeee, eeeeeeeeeeeee, eeeeeeee eeeeeeeee, eeeeee, eee eeeeeeeeee eeee eee eeeeeee eeee e eeeee eeeee ee eeeee-eeeeeeeee eeeeeeee eee eeeeeee eeeeee ee eeee eeeeeeeee eeeeeeeeeeeeee eeeeeeee eeee ee ‌88‌ ee eeee ee eeeeeeeee eeeeee eee eeee eeee eeeeeeeeeeeeeeee (‌Meeeee 88‌).

‌Meeeee 88‌ Meee-Meeeeeeee Meeeeeeeee ee M—M Meeee[‌888‌]

‌Meeeeeeeeee 88‌

Mee Meeee eeeee eee eeeeeeeee eee eeeeeeee ee α-eeeeeee eeeee eeeeeee eeeeeeeeeeeee­eeeeeeeeeeeee ‌88‌ eeee Meeeeeee eeeeeeee.[‌888‌,‌888‌] Me eee eeeeeeee ee e eeeeeeeee eeeeee ee eeee(MM) eeeeeeee, eee eeeeeeee eeeeeeee ee e eeeeeeeeeeeeee eeeeee eee eeeee eee eeeeeeeeeeeee eeeeeeee ‌88‌ ee eeee eeeeee (‌Meeeee 88‌).

‌Meeeee 88‌ Meee-Meeeeeeee Meeeeeeee ee Meeeeeee Meeeeeee[‌888‌]

‌Meeeeeeeeee 88‌

M8	M8	MeMe8 (eee%)	Meeee (%)	ee (%)	Mee
Me	Me	8	88	88	[‌888‌]
Me	eMe	8	88	88	[‌888‌]
Me	Me	88	88	88	[‌888‌]
Me	Me	8	88	88	[‌888‌]
Me	Me	8	88	88	[‌888‌]
Me	Me	8	88	88	[‌888‌]
	Me	88	88	88	[‌888‌]
MM8MMe	Me	88	88	88	[‌888‌]

Meeeeeee eee ee-eeeeeee eeeeeeeeeee eee eeeeeeeeee ee eeeeeee eee eeeeeeeee eeee Meeeeeee eeeeeeee, e.e. ee eeee eeeeeeee ‌88‌ (‌Meeeee 88‌).[‌888‌,‌888‌] Mee eeeeeeee eeeeeeee eeee ee eeeeeee eeee(MM) eeeeeeee, eee eee eeeeeeee ee eeeeeee eeeeeeee eee [(eeeeeeeeeeeeee)eeeeee]eeeeeeeee eeeeeeee eee eeeeeee eee eeeeee ee eeeee eeeeeeeee (‌Meeeee 88‌).[‌888‌,‌888‌] Mee eeeeeeeee eee eeee eeeeeeee ee eeeee eee eeeee, eee eeee eeee Meeee‘e eeeee eee eeeeee eee eeeeeeeee ee e eeeeeeeee–eeee eeeeeee ee eee eeeeeeee eeeeeeeeeeee.[‌888‌,‌888‌]

‌Meeeee 88‌ Meee-Meeeeeeee Meeeeeeee ee Meeeeeee Meeeeeee eeee Meeeeee[‌888‌–‌888‌]

Me eeeeeeee, eee eeeee ee Meee eee eeeeeeeee eee eeee(MM) eeeeeee eeeeeeeee eeeeeeeee ee eeeeeeeeeeeeeeee.[‌888‌] Meeeeee eeeeeeeeeeeeeeee eee eeeeeeee eeee eeeeeeeeeee eeeeeeeee eee eeeeeeee eeeeeee eeeee eeee eeee eeeeeeee eeeeeeeeee. Mee eeeeeeeeeeeeeee eeeeeee eeeeeeeeeee eeeeeeeee eee eeee(MM) eeeeeee ee eeeeeeee eeee(MM) eeeeeeeee ee eeeeeeee ee e eee eeeeeee ee eeeeeeee eee eeeeeeeee eeeee. Mee eeeeeeeeee ee eeeeeeee eeeeeee eee eeee eeeeeeeee. Meee M,M-eeeeeeee(eeeeeeeeeeeeee)eeeee[‌888‌] eee eeeeeeeeeeeeee eeeeeeeee­eeeeeeeeeeeeeeee[‌888‌] eee eeeeeeeee eeeeeeeeee eeeeeeee ee eee eeeeeeee ee eeee eeeeeee. M eeeeee ee eeeeeeeeeeeeee eeee eeeeeeee ee eeee eeeeee eeeee eeee eee eeeeee eeeeeeeeee. Meeeeee eee eeeeeeeeeeeeee ee eeeeeeee eeeeeee ee eeeeeeeeeeee,[‌888‌] eee eeee-eeeeeeeee eeeeeeeeeee ee eeeeeeeeeeeeee eeeeeeeeeeeeeeeeee eeee eeeeeeeeeeeee eee eeeeeeeeeeeeeee eeeeeeee eee eeee eeeeeeeee.[‌888‌] Meeeeeee, eeeee eeeeee eee eeeee eeeeee eee eeee eeeeeeeeeee ee eee eeeeeeee ee eeeeeeeeee eeeee eee eeeeeeee eeee eeeeeee ee eee eeeeeeee ee e eeeeeeeee eeeeee ee eeee(MM) eeeeeeee, eeee eeeeeee ee eeeeeeee ee eee eeee eeeeeeeee.[‌888‌,‌888‌]

Meeeeeeeeeee Meeeeeeee

M-[8-(8,8-Meeeeeeeeee-8-ee)-8-eeeeeeeeeeeeeeee]-8-eeeeeeeeeeeeeeeeee (‌88‌, M8 = M; M8 = 8,8-Meeeeeeeeee-8-ee); Meeeeee Meeeeeeee:[‌888‌]

Me eee eeee ee α-eeeeeeee-8-ee eeeeeee ‌88‌ (888 ee, 8 eeee) ee eeeee MM8Me8 (88 eM) eee eeeee MeMe8 (88 ee, 8.8 eeee). Mee eeeeeee eee eeeeeee ee ee eeeee eeeee eee 8 e eee eee eeeeeeee eee eeee eeeeeeee eeee M8M (8 eM). Mee eeeeeee eeeee eee eeeeee eeee eeeee (8 eM), eeeee (Me8MM8), eee eeeeeeeeeeee. Meeeeeeeeeee ee eee eeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, eeeeeeeee/MeMMe/MM8Me8 8:8:8.8) eeeeeeee eeeeeeeee eeeeeeee; eeeee: 888 ee (88%); 8M MMM (888 MMe, MMMe8, δ): 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88 (e, 8M), 8.88 (e, 8M), 8.88 (e, M = 88.8 Me, 8M), 8.88 (e, M = 8.8 Me, 8M), 8.88 (ee, M = 8.8, 8.8 Me, 8M), 8.88 (e, 8M), 8.88 (e, M = 8.8 Me, 8M), 8.88 (e, M = 8.8 Me, 8M), 8.88 (e, M = 8.8 Me, 8M), 8.88 (e, M = 8.8 Me, 8M); 88M MMM (888 MMe, MMMe8, δ): 88.8, 88.8, 88.8, 88.8, 88.8, 88.8, 88.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8.

8-(8-Meeeeeeeeeee)eeeeee-8,8-eeeee [‌88‌, M8 = (MM8)8Me; M8 = 8-MeM8M8]; Meeeeee Meeeeeeee:[‌888‌]

Me e eeeee eeeeeeee eeee eee eeeee MeM8 (8.8 eeee). Mee eeeeeeee eeee eee eeeee eeeee eeeeeee eeeeeeee eeee e eeeeeee eee. Meee, eee eeeeeeee (8.8 eeee), eee eeeeee (8.8 eeee), eeeeeeeeee (8.8 eeee), eee eeeeeee (8, 8, ee 8 eM) eeee eeeee eeeeeeeeeeee eeee eee eeeee eeeeeeee eeee eeeeeeee eeee e eeeeee eeeeeeeee eeeee eeeee, eee eee eeeeeeeee eeeeeee eee eeeeeee ee 888 °M. Meee eee eeeeeeee eee eeeeeeee ee eeeeeeeee ee MMM (ee MMM), eee eeeeeee eee eeeeee ee ee eee eeee eeeeeeee. Meeeeeeeeee eee eeeeee eeeeeeeeeeeeee (eeeeee eee, eeeeeeeee eeeee ee eeeeeeeee eeeee/MeMMe) eeeeeeee eee eeeeeeeeeeeee 8,8-eeeeeeeeeeeee eeeeee; eeeee: 88%; MM (eeee) ν̃eee: 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888 ee−8; 8M MMM (888 MMe, MMMe8, δ): 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 88M), 8.88 (e, M = 8.8 Me, 8M); 88M MMM (88 MMe, MMMe8, δ): 888.8, 888.8, 888.8, 888.8, 888.8, 88.8, 88.8, 88.8, 88.8, 88.8, 88.8, 88.8, 88.8, 88.8, 88.8.

8,8-Meeeeeeee ‌88‌; Meeeeee Meeeeeeee:[‌888‌]

Me e eeeeeee ee e eee eeeeeee (8.8 eeee) eee e eeeeeeeee eeeeee ee eeee(MM) eeeeee (8.8 eeee) ee eeeee MMM (8 eM) eee eeeee eee α-eeee eeeeee (8.8 eeee) eeeee M8. Mee eeeeeee eee eeeeeee eeeee eee eeeeeeee eeeeeeeeee eeeee ee eee[‌888‌]. M8M (8 eM) eee eeee eeeee ee eee eeee. Me8M (88 eM) eee 88% ee MM8M (88 eM) eeee eeeee eee eee eeeeeeeee Me8MeM eee eeeeeee ee eeeeeeeeee. Mee eeeeeeee eee eeeeee eeee M8M (8 × 88 eM), eeeee (MeMM8), eee eeeeeeeeeeee. Mee eeeeeeeee eeeeeee eee eeeeeeee ee eeeee eeeeee eeeeeeeeeeeeee.

8-Meeee-8,8e,8,8e-eeeeeeeeee-8M-8,8-eeeeeeeeeeeeeee-8e-eeeeeeeeeeee [‌88‌, M = MMe; MMM = MMM; M8 = M8 = M8 = M8 = M; M8,M8 = (MM8)8]; Meeeeee Meeeeeeee:[‌888‌]

Me e eeee ee 8-eeeee-8M-eeeeee-8-eeeeeeeeeeee (8.88 e, 8.8 eeee) ee eeeee MM8Me8 (8.8 eM) ee ee eee eeeee e 8 M eeee ee MeMe8 ee eeeee MMM (88 μM). Mee eeeeeee eee eeeeeee eee 88 eee. M 8.88 M eeee ee eeeeeeeeeeee ee eeeee Me8M (888 μM) eee eeeeeeeee eeeeeeeee-8,8-eeeee (888 μM, 8.8 eeee) eeee eeee eeeee ee eeee eeeeeee eeee. Mee eeeeeeeee eeeeeee eee eeeeeeeeeee eeee e eeee-eeeeeeee eeeeee eee eeeeeeeeee ee 88 eeee ee 88 °M. Meeee 88 e eee eeeeeeeeeeeee, eee eeeeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Meeeee eeeeeeeeeeeeee ee eee eeeeeee (eeeeee eee, eeeeeee/MeMMe 8:8) eeee eee eeeeeee; eeeee: 88 ee (88%).

Meeeeeee 8-Meeeee-8-eeeeeeeee-8-eeeeee-8,8,8,8-eeeeeeeeee-8M-eeeeeeeee-8,8-eeeeeeee­eeeee (‌88‌, M8 = Me; M8 = Me); Meeeeee Meeeeeeee:[‌888‌]

(M)-8-Meeeeeeeeeeeeeeeee-8,8-eeeeeeeeeeeee (88% ee; 88 ee, 8.88 eeee, 8 eeeee) eee 8-eeeeeee-M-eeeeee-8M-eeeeee (88 ee, 8.88 eeee, 8.8 eeeee) eeee eeeeeeeee ee 8,8-eeeeeeeeeeeeee (8 eM). Me(MMe8)8 (88 ee, 8.888 eeee, 8.88 eeeee) eee eeee eeeee eee e eeeeee eeeeeeeee eee eeeeeeee. Mee eeeeeeee eeeeee eee eeee eeeeee eeee eeeee eee eee eeeeeee eee eeeeeee ee eeeeee. Meee eeeeeeeeee (MMM), eee eeeeeee eee eee eeeeee eee eeeeeeee ee eeeee eeeeee eeeeeeeeeeeeee (MeMMe/eeeeeee) ee eeeee eee eeeeeee eeeeeee ee e eeee eeeeee eeee; eeeee: 888 ee (88%); Me 8.88 (MeMMe/eeeeeee 88:88); 88% ee ee eeeeeeeeee ee eeeeee MMMM [Meeeeeeee MM-M, 888 × 8.8 ee8, eeeeeee/eMeMM 8:8, 8 eM·eee−8, 888 ee; eM = 88.88 (+) eee 88.88 eee (–)]; MM (eeee eeee) ν̃eee: 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 888, 888, 888, 888, 888 ee−8; 8M MMM (888 MMe, MMMe8, δ): 8.88–8.88 (e, 8M), 8.88 (eee, M = 8.8, 8.8, 8.8 Me, 8M), 8.88 (e, M = 8.8 Me, 8M), 8.88 (e, 8M), 8.88 (e, 8M), 8.88 (ee, M = 88.8, 8.8 Me, 8M), 8.88 (e, 8M), 8.88 (e, 8M), 8.88 (e, 8M), 8.88 (ee, M = 88.8, 8.8 Me, 8M), 8.88 (ee, M = 88.8, 88.8 Me, 8M); 88M MMM (888 MMe, MMMe8, δ): 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 88.8, 88.8, 88.8, 88.8, 88.8, 88.8.

Meeeeeeeeeee ‌88‌; Meeeeee Meeeeeeee:[‌888‌]

Me e Meeeeee eeee eeee eeeee eee 8-eeeeeeeeeeeeeeeeeee (8.8 eeee), eee eeeeee (8 eeeee), MeMe8 (88 eee%), eee 8,8-eeeeeeeeeeeeee (8 eM). Mee eeee eee eeeeeee eeee eeeee, eee eee eeeeeee eee eeeeeee ee 88 °M eeeee eeeeeeee eeeeeeeeeee ee eeeeeeee eeeeeeee, ee eeeeeeeee ee MMM eee MM/MM eeeeeeee. Meeee eee eeeeeeee eee eeeeeeee, eee eeeeeee eee eeeeee ee ee, eeeeeee eeee Me8M, eee eeeeee eeee eeeee. Mee eeeeeee eeeee eee ee-eeeeeeeee eeee MeMMe. Mee eeeeeeee eeeeeee eeeeeeee eeee eeeee (MeMM8) eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeeeee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee) ee eeeeee eee eeeeeee eeeeeee.

Meeeeee 8-Meeeee-8-eeeeeeeeeeeeeeeeeeee-8,8-eeeeeeeeeeeee (‌88‌, M = MM8; M8 = M; M8 = Me); Meeeeee Meeeeeeee:[‌888‌]

Meeeeee 8-[eeeeee(eee-8-eeee)eeeee]eeeeeeee (888 ee, 8.8 eeee, 8.8 eeeee) eee MeMe8 (8 ee, 8.88 eeee, 88 eee%) eeee eeeeeeeee ee 8,8-eeeeeeeeeeeeee (8 eM) eee eeeeee ee 888 °M ee e eeeeee eeee eee 88 e. Mee eeeeee eeeeeee eee eeeeeeee eeeeeee eeeeee eee (Me8M) eee eee eeeeeee eee eeeeeee. Mee eeeeeee eee eeeeeeee ee e eeeee eee eeeee eeeeeeeeeeee ee eeeee eeeeee eeeeeeeeeeeeee (eeeeeeeee eeeee/Me8M 8:8); eeeee: 888.8 ee (88%); MM (eeee) ν̃eee: 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 888, 888, 888 ee−8; 8M MMM (888 MMe, MMMe8, δ): 8.88–8.88 (e, 8M, Mee), 8.88–8.88 (e, 8M, Mee), 8.88, 8.88 (e, 8M, Mee), 8.88 (e, 8M, M = 8.8 Me, MMMM), 8.88 (e, 8M, M = 8.8 Me, MMM), 8.88 (ee, 8M, M = 88.8, 8.8 Me, MMMM), 8.88 (ee, 8M, M = 88.8, 8.8 Me, MMMM), 8.88 (e, 8M, MM8Me), 8.88 (e, 8M, M = 8.8 Me, MM8M), 8.88 (ee, 8M, M = 8.8, 8.8 Me, MM8MM), 8.88 (e, 8M, M = 8.8 Me, MM8); 88M MMM (888 MMe, MMMe8, δ): 888.8 (8 × MM), 888.8 (Mee), 888.8 (Meeeeee), 888.8 (8 × MMee), 888.8 (8 × MMee), 888.8 (MMee), 888.8 (MM8-eeeeee), 88.8 [M(MM)8], 88.8 (8 × MM8), 88.8 (MM8Me), 88.8 (MM8M), 88.8 (MM8), 88.8 (8 × MM8).

8-Meeeeeeeeee 8,8-Meeeeeeeee Meeeeeeee ‌88‌; Meeeeee Meeeeeeee:[‌888‌]

Me e eeee ee eee 8-eeeeeeeeeeeeeeeeee (8.88 eeee) ee MM8Me8 (8.88 eM) eeee eeeee eee 8,8-eeeeeeeeee eeeeeeee (8.88 eeee), MMMMe (8.8 ee, 8.8 µM, 8.888 eeee), eee MeMe8 (8.8 ee, 8 eee%). Mee eeeeeeeee eeeeeee eee eeeeeee ee ee eeeee ee eeeeeee eeeeeeeeeeeeee eee eeeeeeee (MMM), eee eeee eeeeeeee ee eeeee eeeeee eeeeeeeeeeeeee (eeeeee eee, eeeeeeeee eeeee/MeMMe 888:8 ee 88:8) ee eeee eee eeeeeee eeeeeee.

eeee-Meeee (M)-8-[(M)-eee-Meeee]eeeeeeeee [‌88‌, M8 = (M)-MMMeMe; M8 = Me]; Meeeeee Meeeeeeee:[‌888‌]

M eeee ee eeeee MeMe8 (8.8 ee, 8.8 eee%) ee eeeee MMM (8 eM) ee 8 °M eee eeeeeee eeeeeeeeeeee eeee eeee-eeeee (8M,8M)-8-eeeeee-8-[(eeeeeeeeeeeeeeeeeeeeeee)eee]eeeeeeeeee [‌88‌, M8 = (M)-MMMeMe; 888 ee, 8.88 eeee] eee e 8.8 M eeee ee MeMeMe ee MMM (8.88 eM, 8.8 eeee, 8.8 eeeee) eeeee eeeee. Meeee eee eeeeeee eee eeee eeeeeee eee 8 e ee eeee eeeeeeeeeee, ee eee eeeeeee eeee eeeeeee eee eeeeeeee ee eee eeeeeeee ee eee. ee MM8Me. Mee eeeeeee eee eeee eeeeeeeee eeee eeeeeee (8 ×), eee eee eeeeeeee eeeeeee eeeeee eeee eeeeeee eeeeeeee ee e eee ee eeeeee eee. Mee eeeeee eee eeeeee eeee eeeeeee, eee eeeeeee eee eeeeee eeee e eeeeeee ee eeeeeee/Me8M (88:8), eee eee eeeeeee eee eeeeeeeee eee ee eeeeeeeeeee eeeeeeee; eeeee: 88%; 88% ee.

8,8-Meeeeeeeeeeeee-8-ee (‌88‌, M8 = M8 = Me; M8 = Me); Meeeeee Meeeeeeee:[‌888‌]

Me e 8.8 M eeee ee MeMeMe ee MMM (8.88 eM, 8.88 eeee) eee eeeee MeMe8 (88.8 ee, 8.88 eeee) ee ee eeeee M8. Mee eeee eee eeeeeee ee ee eee 8 e, eee eeee eeeeee ee 8 °M eee eeeeeeeeeeee (888 ee, 8.88 eeee) eee eeeee ee 8 °M. Mee eeeeeee eee eeeeeee ee 8 °M eee 8 e, eee eee eeeeeeee eee eeeeeeeee ee MMM. Mee eeeeeeeee eeeeeee eee eeeeeeee ee eee. ee MM8Me (8 eM), eeeeeeeee eeee MeMMe (8 × 88 eM), eee eeeeee eeee eeeee (8 eM). Mee eeeeeeee eeeeeeee eeee eeeee (MeMM8). Mee eeeeeee eeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee eee eee eeeeeeeee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeeee eeeeee eee, eeeeee/MeMMe) ee eeee eee eeeeeee eeeeeee; eeeee: 888 ee (88%).

References