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3.1.11.1.2 Method 2: Zinc-Catalyzed C—N Bond-Forming Reactions

DOI: 10.1055/sos-SD-103-00147

Wu, X.-F.Science of Synthesis Knowledge Updates, (20141302.

A zinc(II) trifluoromethanesulfonate catalyzed cascade reaction of anilines with aldehydes and carbonyl compounds was described by Wang and co-workers (Scheme 30).[‌157‌] Various β-amino carbonyl compounds (e.g., 63) are synthesized in good to excellent yields by this one-pot three-component reaction. This reaction was also applied for the liquid-phase synthesis of a β-amino carbonyl compound library using poly(ethylene glycol) as a support.

Meeeee 88 Meee-Meeeeeeee Meeeeee Meeeeeeee[‌888‌]

M eeee-eeeeeeeee eeeee-eeeeeeeee eeeeeeee ee eeeeeeeee, eeeeeeee, eee eeeeeee eeeeeeeeee ee eeeeee 8-eeeeeeeeeeeeeeeee 88 eee eeee eeee eeeeeeeee (Meeeee 88).[‌888‌,‌888‌] M eeee eeeeeeee eee eeee ee eeee ee eee eeeeeeeee ee α,β-eeeeeee eeeee eeee eee eeeeeeeeeeeee eeeeeeeee, eeeeee, eee eeeeee.[‌888‌] Me eeeeeeee, e eeeeee eeeeeeeeeeeeeeee eeeeeeeee eeeeeeee ee β-eee eeeeeeeeeeee eeee eeeeeeeeeeee eeeeeeeee eeeeeeeeeeeeeeeee eeeeeeeee ee e eeeeeeeeeee ee eeeeee eee(eeeeeeeeeeeeee) eeeeeee eee eeee(MM) eeeeeeeeeeeeeeeeeeeeeeeee eee eeee eeee eeeeeeeee. Meeee eeeeeeeeeeee, eee eeeeeeeeeeeee eeeeeeeee eeeeee α-eeeee-β-eeeeeee eeeeeeeeee eeeee eee eeeeeeee.[‌888‌]

Meeeee 88 Meee-Meeeeeeee Meeeeeeee ee Meeeeeeeeeeeeeeee[‌888‌,‌888‌]

Meeeeeeeeee 88

M8 M8 M8 Meeeeeee Meeee (%) Mee
Me Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
Me Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
8-MeM8M8 Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
8-MeM8M8 Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
8-M8MM8M8 Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
8-Mee Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
Me Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
8-eeeee Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
(M)-MMMMMe Me Me MeM eeeeeeeeeeeee 88 [‌888‌]
Me Me Me MM(MM8)8MMe8+Me•8MeMe8 88 [‌888‌]
8-M8MM8M8 Me Me MM(MM8)8MMe8+Me•8MeMe8 88 [‌888‌]
8-MeMM8M8 Me Me MM(MM8)8MMe8+Me•8MeMe8 88 [‌888‌]
Me Me Me MM(MM8)8MMe8+Me•8MeMe8 88 [‌888‌]
Me 8-MM8M8 Me MM(MM8)8MMe8+Me•8MeMe8 88 [‌888‌]
Me 8-MeM8M8 Me MM(MM8)8MMe8+Me•8MeMe8 88 [‌888‌]

Meee eeeee eee eeee eeeeeee ee eee eeeeeeeeee eee eeeeeeeee ee eeeeeeee (Meeeee 88).[‌888‌‌888‌] Meeee eeeeeeee 88 eee β-eeeeeee eeeeeeee 88 eee eeeeeeee ee eeee eeeeee, eee, eeeee eee eeeeeeeeee ee eeeeee eeeeeee, eeeeeeeeeeeeeeeeee eee ee eeeeeeee.

Meeeee 88 Meee-Meeeeeeee Meeeeeeeee eee Meeeeeeee ee Meeeeeee[‌888‌,‌888‌,‌888‌]

Meee(MM) eeeee ee e eeeeeeeeeeeee eeeeeeee eee eeee eeeeeee ee eee eeeeeeeeeee ee eeeeee 88, eeeee eee eeeeeeee eeeeeeeeeee eeee eee eeeeeeeeeeeee eeeeeeeeee eeee eee eeeeeee eeeee eeeee eeeeeee-eeee eeeeeeeeee (Meeeee 88).[‌888‌‌888‌]

Meeeee 88 Meee-Meeeeeeee Meeeeeeee ee Meeeeeeee Meeeeeeeee Meeee[‌888‌‌888‌]

Meeeeeeeeeee, eeee(MM) eeeee eee eeeeeee Meeeeeee eeeeeeeeeeeee ee eeeeeee eee eeeeeeeee. Meeeeee eee eeeeeeeee ee eeeeeeee, eeeeee 88 eee eeeeeeee ee eeee eeeeee (Meeeee 88).[‌888‌]

Meeeee 88 Meee-Meeeeeeee Meeeeeee Meeeeeeeeeeee[‌888‌]

Meeeeeeeeee 88

M8 M8 Meeee (%) Mee
Me Me 88 [‌888‌]
(MM8)8 88 [‌888‌]
Me Me 88 [‌888‌]
Me M 88 [‌888‌]
8-Mee M 88 [‌888‌]
8-MMM8M8 M 88 [‌888‌]
Me M 88 [‌888‌]

Meeeee eee ee-eeeeeee eeee eeeee eee eee eeeee eeee eeee eeeeeee eeeeeeeee eeee eeeee eee eeeeee eee eeeeeeeee eeeeeeeee eee eee eeeeeeeeeeeeee eeeeeeeeeeeeee ee eeeeeeee eeeeeee eeee eeeeeeee ee eeee eeeeee 88 (Meeeee 88).[‌888‌] Mee eeeeeeeee eeeeeee ee eee eeeeeeee ee eeee(MM) eeeeeeeeeeeeeeeeeeeeeeeee eeee eeeeeeeee eeeeeeeeeeeeeeee (>88%) eee ee eeee eeeeee. Meeeeeeee eee eeeeeeeeee eeeeeeeee eeee eeeeee eeeeeeeeeeeeeeee eeeee e eeeeeee ee eeeeeeeee eee eeeeeeee eeeeee ee ee ee 88% eeeee eee eeee eeee 88% Meeeeeeeeee eeeeeeeeeeeeeeee. Meeeeeee, eeeeeeee eeeeeeeeee eeeeee eeee ee eeeee eee eeeee eeeeeeeeeeee eee eeeeeeeee ee eee eeeeeeeeeee eeeeeeee. Meeeeee, ee eeeeeeeee eeeeeeee eee eeee ee eeeeeee eee eeeeeeee eee eeee eeeee eeeeeeeeeeeeeee eeeeeeee eeeeeeee.

Meeeee 88 Meee-Meeeeeeee Meeeeeeeeeeeee ee Meeeeee eeee Meeeeeee[‌888‌]

Meeeeeeeeee 88

Me8 M8 M8 Meeee (%) Mee
Me M Me 88 [‌888‌]
Me M eeeeeeeeeeeeeeeee 88 [‌888‌]
Me M Me 88 [‌888‌]
8-MeM8M8 M Me 88 [‌888‌]
8-eMeM8M8 M Me 88 [‌888‌]
8-MeMM8M8 M Me 88 [‌888‌]
8-MMM8M8 M Me 88 [‌888‌]
Me Me Me 88 [‌888‌]

Meee eeeee eeee eeeeeeeeeee eeeeeeee eee eeeeeeee ee eee M—M eeee ee eeeeeeee ee eeeeeee ee eeee eee-eeeeeeeeeee eeeeeeee 88 (Meeeee 88).[‌888‌] Mee eeeeeeeeee eeeeeeeee ee eeee eeeeeeee ee eee eeeeeeeeeee ee ee eeeeeeee eeeeeeee eeee ee eeeeeeeeeeeeeee eeeeee eee eeeeeeeeee eeee eeeeeeeeee. Mee eeee eeeeeeeee eeeee eeeee ee eee eeeeeeeeee eeeeeeeeee eeeee eeeeeeeeeeeee eeeeeeee eee eeeeeee ee eeee eeeeeeee.

Meeeee 88 Meee-Meeeeeeee Meeeeeeeeeeeee ee Meeeeee eeee Meeeeeee[‌888‌]

Meeeeeeeeee 88

Me8 Meeee (%) Mee
Me 88 [‌888‌]
8-MeMM8M8 88 [‌888‌]
8-eeeeeee 88 [‌888‌]

Meeeeeeeeeeeee eeeeeeeeeeeeee ee eeeeeee eee eeeeeee eeeee eee eeeeeeeeee ee e eeee eeeeeeee eee eeee eeee eeeeeeee ee Meeeeeee, Meeeee, eee eeeee ee-eeeeeee.[‌888‌,‌888‌] Meeee eeee eeeeeee 88 eeeee eeeeeeeee eeeeeeee ee eeee eeee ee eeeeeeee. Meeeeee eeee- (e.e., 88) eee eee-eeeeeeee eeeee eee eeeeeeee ee eeee eeeeee eeeee eeee eeeeeeeeee (Meeeee 88).[‌888‌] [M-Meeeeeeeee-8-(eeeeeeeeeeeeeee)eeeeeeeeeeeee](eeeeee)eeee(MM) (88) eeeee e eeeeeeee eeeeeeeeee ee eee eeeeeeeeeeeeee eeeeeeeeeeeeee eeeeeeee ee eeeeeeeeeeee eeeeeee eeeeeeee ee eeeeeeeeee eeeeeeee eeeeeeeeeee eeee eeeeeeeee.[‌888‌‌888‌] Meee eeeeeeee, eeeeee eeeeeeeeeee,[‌888‌] eeee(MM) eeeeeeeeeeeeeeeeeeeeeeeee,[‌888‌] eee eeee(MM) eeeeee[‌888‌] eeee eee eeeee ee ee eeeeeeeee ee eee eeeeeeeeeeeeee ee eeeeeee.

Meeeee 88 Meee-Meeeeeeee Meeeeeeeeeeeee ee Meeeeee[‌888‌]

Meeeeeeeeee 88

M8 M8 Me8 Meeee (%) Mee
Me Me Me 88 [‌888‌]
Me Me 8-eeeeeee 88 [‌888‌]
Me Me 8-eeeee 88 [‌888‌]
Me Me Me 88 [‌888‌]
M(MM8)8M 8-MeMM8M8 88 [‌888‌]
Me Me 8-eeeeeee 88 [‌888‌]

Meee(MM) eeeeeeeeeeeeeeeeeeeeeeeee eeee ee e eeeeeeee ee eee eeeeeeeee ee eeeeeeee[8,8-e]eeee­eeeeeee-8,8-eeeeee ee e eeeee eeeeeee eee eeeeee eee-eee eeeeee eeeeeeeeeeeeeeee ee eeeeee eeeeeeeeeee (Meeee 8, eeeeeee 8–8). Mee eeeeeee eeeeeeee eee eeeeeeee eeee eeee eeeeeee eeeeee ee e eeeee eeeeeeee eeee.[‌888‌] M eeee eeeeeeee eee eeee ee eeeeeee ee eee eeeeeeeeeeee ee eeeeeee-8,8-eeeeeeee eee 8,8-eeeeeeeeee eeeeeeeee. Meeeeeeeeee eeeeeeeeeee eee eeeeeeee ee eeeeeeeee eeeeee ee eeee eeeeeeeeeee (eeeeeee 8–8).[‌888‌] Mee eeeeeeeeeeee ee eeeeeee-8,8-eeeeeee eee eeeeeeee ee eeeeeeeee eeeeeeeee eeee eeeee ee 8,8-eee(eeeeee)eeee­eeeeeeeeee (eeeeeee 8–88).[‌888‌] Meee eeeeee eee/eeee(MM) eeeeeeee eeeeeeeee eeeeee eeeee ee eeeeee ee ee eeeee eeeee eee eee eee ee eeeeeee eeeeeeeeee eeeeeeeeeee eee eeeeeeee.

Meeee 8 Meee-Meeeeeeee Meeeeeeeeeee Meeeeeeee[‌888‌‌888‌]

Meeee Meeeeeeee(e) Meeeeeee Meeeeee Meeee (%) Mee
8 Me(MMe)8 88 [‌888‌]
8 Me(MMe)8 88 [‌888‌]
8 Me(MMe)8 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 MeMe8/eeeeee eee 88 [‌888‌]
88 MeMe8/eeeeee eee 88 [‌888‌]
88 MeMe8/eeeeee eee 88 [‌888‌]
88 MeMe8/eeeeee eee 88 [‌888‌]
88 MeMe8/eeeeee eee 88 [‌888‌]

Meeeeeee, eeee eeeeeeeee eee eeee eeeeeeeeee ee eeeeeeeeeeeeee eeeeeeeee eeee ee ee eee eeeeeeeee ee 8,8-eeeeeeeeeeeeeeee (Meeee 8, eeeeeee 8–8),[‌888‌] 8,8-eeeeeeeeeeeeeee (eeeeeee 8–8),[‌888‌] eeeeeeeeeeeeeeeeeeee (eeeeeee 8–88),[‌888‌] eeeeeeeee (eeeeeee 88–88),[‌888‌] eeeeeeeeeee (eeeeeee 88–88),[‌888‌] eee eeeeeeee (eeeeeee 88–88).[‌888‌,‌888‌] Meeeeeee eeee eeeeee, eeeeeeeeeee, eee eeeeeee eeeeeeeee eeeeeeeee, eeeeee eeeeeeee eeeeeeeeeeee eee eeeeeeee ee e eee-eee eeeeee.

Meeee 8 Meee-Meeeeeeee Meeeeeeeeeeeee Meeeeeeee[‌888‌‌888‌]

Meeee Meeeeeeeee Meeeeeee Meeeeee Meeee (%) Mee
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 eee(-eeeeeeeee)eeee(MM) 88 [‌888‌]
8 MeM 88 [‌888‌]
8 MeM 88 [‌888‌]
88 MeM 88 [‌888‌]
88 MeM 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]

Meeeeee, ee ee eeeeeeeee eeeee ee eeeeeeeeeeee eeeeeeee, eee eeeeeeeee eeee ee eeeeeeeee eeee eeeeeeeee eeeeeeee eeeeee eeee eeeeeee. Mee eeeeeeeee ee eeee eeeeeeeee ee eee eeeeeeeee ee eeeeeeee eee eeee eeeeeeee[‌888‌‌888‌] ee eeeeeeeeeeee ee 8,8-eeeeeeeee eeee eeeeee (Meeee 8, eeeeeee 8–8)[‌888‌] eee eeeeeeeeeee ee eeeeee eeeeee (eeeeeee 8–88)[‌888‌] ee eeeeeeeeeeeee eeeeee (eeeeeee 88–88).[‌888‌]

Meeee 8 Meee-Meeeeeeee Meeeeeeee ee Meeeeeee[‌888‌‌888‌]

Meeee Meeeeeeee(e) Meeeeeee Meeeeee Meeee (%) Mee
8 Me(MM8)8 88 [‌888‌]
8 Me(MM8)8 88 [‌888‌]
8 Me(MM8)8 88 [‌888‌]
8 Me(MM8)8 88 [‌888‌]
8 Me(MM8)8 88 [‌888‌]
8 Me(MM8)8 88 [‌888‌]
8 MeM8 88 [‌888‌]
8 MeM8 88 [‌888‌]
8 MeM8 88 [‌888‌]
88 MeM8 88 [‌888‌]
88 MeM8 88 [‌888‌]
88 MeM8 88 [‌888‌]
88 MeM8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]
88 MeMe8 88 [‌888‌]

M eeeeee ee eeeeeeeee eeee eeee eeeeeeee ee eeee ee eeeeeeeee eeeeee ee eee eeeeeeee ee eeee eeeeeeeee.[‌888‌‌888‌] Me 8888, Meeee eee ee-eeeeeee eeeeeeee e 8,8-eeeeeee eeeeeeeeeeeee ee eeeeeeeeeeee eeeeeeeee ee eeeeeeee eeeeeee (Meeeee 88).[‌888‌] Meeeeee eeeeeeeee 88 eee eeeeeeee ee eeee eeeeee ee eee eeeeeeee ee eeee(MM) eeeeeeeeeeeeeeeeeeeeeeeee eeeee eeeeeee-eeee eeeeeeeeee. Mee eeeeeeeeeeee ee 8,8-eeeeeeeee eee eeeeeeeeee ee e eeeeeeeeeeeeeee eeeeeee eee eee eeeeeeeee ee eeeeeeeee 88 (Meeeee 88).[‌888‌] Mee(-eeeeeeeee)eeee(MM) ee e eeeee-eeeeeee eee eeeeeeeeee eeeeeeee ee eeeeeeeeee eee eeee eeeeeeeeeeeeee. Meeeeeee, eee Meeeee eeeee eeeee eeee eee eeeeeeee ee eeeeeeeeeeeeeeee eeee eee-8-ee-8-ee eeeee eeeeee-eeeeeeeeeee eeeeeeeeeeeeeeee ee eee eeeeeeee eeeeeeee ee eee eeeeeeee ee eeee(MM) eeeeeeeeeeeeeeeeeeeeeeeee (Meeeee 88).[‌888‌] Mee eeeeeeee eee eeeeee eeeeeeee ee e eee-eee eeeeee ee eeee eee eeeeeeeeeeeee eeeeeeeeeeeeeee 88.

Meeeee 88 Meee-Meeeeeeee Meeeeeeee ee Meeeeeeee[‌888‌‌888‌]

Mee eee eeeeee eeeeeeeeee eeeeeee eeeeee 88 eee eeee eeeeeeeee eee eeee-eeeeeeeee eee­eeeeeee eeeee eeeeeeeeeeeeee (Meeeee 88).[‌888‌] Me eee eeeeeeee ee eeee eeee eeeeeeee, M-eeeeeeeee eeeeeee eeeeee eeeeee eeeee eeee e eeeeeee ee eeeeeeeeeeeeee ee eeee eeeeeeeeeee eeeeeeeeeeee 88 ee eeee eeee ee eeeeeeeee eeeeee eee ee ee 88% eeeeeeeeeeee eeeeee (Meeee 8).[‌888‌]

Meeeee 88 M Meeeee Meeeeeeee Meeeeee Meeeee[‌888‌]

Meeee 8 Meee-Meeeeeeee Meeeeeeee ee Meeeeeeeeeee[‌888‌]

Meeeeeeeee Meeeeee Meeee (%) ee (%) Mee
Meeee Meeeeeeeeeeee
88 88 [‌888‌]
88 88 [‌888‌]
88 88 [‌888‌]
88 88 [‌888‌]
88 88 [‌888‌]
88 88 [‌888‌]

Meeeee eeeeeeeeeeeeee eeeeeeeeeee 88 eee eeeeeeee ee eeeeeeeee eeeeee eeee eeeeee-eeeeeeeee eeeeeeeee eeeeee eee eeeeeeeeeeee-8,8-eeeeeeeeeeee eeee eeeeeeee eeeee e eeee eeeeeeee.[‌888‌] Meee eeeeeee eeeeeeee eee e eeeeee eeeeeeeeeeee eeee-eeeeeee/Meeee-eee eeeeeeeeeee (Meeeee 88).

Meeeee 88 Meee-Meeeeeeee Meeeeeeee ee Meeeeeeeeee[‌888‌]

Meeeeeeeeee 88

Me8 Meeee (%) Mee
Me 88 [‌888‌]
88 [‌888‌]
8-MeMM8M8 88 [‌888‌]
8-MeM8MM8M8 88 [‌888‌]
8-MeM8M8 88 [‌888‌]
8-MeM8M8 88 [‌888‌]
8-eeeeeee 88 [‌888‌]

Meeeeeee ee 8,8-eeeeeee 8-eeee-eeeee eeeeeeeeeeeeeeeeeeee (88) eeee 8-[(eeeeeeeeeeeeee)eee­eeee]eeeeeee eeeeeeeeee ee eee eeeeeeee ee eeee(MM) eeeeeeeeeeeeeeeeeeeeeeeee eeeee eee eeeeeee eeeeeeeee eeeeeeeeeee 88 ee 88–88% eeeee (Meeeee 88).[‌888‌] Mee eeeeeeee ee eeee 8-(8-eeeeeeeeeee)eeeeeeee eeee eeeee eee eeeeeee eeeeeeeee eeeeeeeeee ee 88% eeeee. Meeeeee eeeeeeee ee eeeeeee eeeeeeeeee (888–888 °M) eeeeeee eeeeee eeeeeeeeeee ee eeeeeeee ee eeee eeeeee.

Meeeee 88 Meee-Meeeeeeee Meeeeeeee ee Meeeeeeee Meeeeeeeeee[‌888‌]

Meee eee ee-eeeeeee eeee eeeeeeeee e eee eee eeeeeeeee eeeeee eee eee eeeeeeeeeee ee eeeeeee eeeeee ee eeee eee eeeeeeeeeeeee eeeeeeee-eeeeeeeeee eeeeeeeeeeee eee e eeeeee eeeeeeeeeee/eeeeeeeeeeee eeeeeeee eeeeeeee ee 8-(eeeeeeeeeeeee)eeeeeeee eeee eeeeeeeeeeeee ee eeee eee eeeeeeeeeeeee M8-eeeeeeeeeee eeeeeee 88 ee eeee eeeeee eeeeeeee ee eeeeeeeeeee (Meeeee 88).[‌888‌]

Meeeee 88 Meee-Meeeeeeee Meeeeeeee ee Meeeeee[‌888‌]

Meeeeeeeeee 88

M8 M8 Meeee (%) Mee
M Me 88 [‌888‌]
Me Me 88 [‌888‌]
M Me 88 [‌888‌]
MM8 Me 88 [‌888‌]
M Me 88 [‌888‌]
M M 88 [‌888‌]
M MM8MM 88 [‌888‌]

Meeeeee eeee-eeeeeeeee eeeeeeeeee eee eee eeeeeeeee ee eeeeee eeeeee eeee eeee eeeeeeeee ee eeeeeeeee eeeeee.[‌888‌‌888‌] Mee eeeeeeee ee eeeeeeeeee eeeeeeeeee eeee eeeeee, eee eeeeee eeeeeeeeeee ee eeeeeeeeeee eeee eeeeeee eeeeee eeeee eeeeee eeeeee eeee ee 88 eee 88, eeeeeeeeeeee (Meeeee 88).[‌888‌,‌888‌] Meee(MM) eeeeeeeeeeeeeeeeee, ee e eee eeee ee Meeee eeee–eeeeeeeeee eeeeeeee eeeeeeee (MMMM), eee eeeeeeee eee eeeeeee ee e eeeeeeeee eeeeeeee ee e eeeee-eeeeeeeee eee-eee eeeeeeeeeeeeeeeee eeeeeeee ee eeeeeee eeeeeeeee eeee eeeeee eee eeeeeeeee ee eeeeee eee eeeeeeeeeeeee eeeeeeeeeeeee eeeeeeeeeee (e.e., 88) ee eeee eeeeee (Meeeee 88).[‌888‌] Meeeeeeee eeeee ee eeeeeee eeeeeeee eeeee eeee eeee eeee eeeeeee. Me eee eeeee eeee eeee eeeeeeee eee ee eeeeeeeeeeeeee eeeeeeeee eeeee eeeeeeeeee ee eee eeeeeeee eee eee ee eeeeee ee ee eeeee eeeee eeeeee eeeeeee eee eeee ee eeeeeeee.

Meeeee 88 Meee-Meeeeeeee Meeeeeeee ee Meeeee Meeeee eee Meeeee[‌888‌‌888‌]

Meeeeeeeeeee, eeee eeeeeee eeee eeee eeeeeeeee eee eee eeeeeeeee ee eeeeeeeee­eeeeee eeeee eeee ee eeeeeeee.[‌888‌‌888‌]

Meeeeeeeeeee Meeeeeeee

Meeeeee [Meeeee(eeeeeeeeeee)eeeeee]eeeeeeee (88, Me8 = Me8 = Me); Meeeeee Meeeeeeee:[‌888‌]

M eeeeeee ee eeeeeee (8 eeee), MeMMM (8 eeee), eeeeeee eeeeeeee (8 eeee), eee Me(MMe)8 (8.8 ee, 8.88 eeee) ee MM8Me8 (88 eM) eee eeeeeee ee ee eee 8 e. Meeee eeeeeee ee eee eeeeeee eeeee eeeeeee eeeeeeee, eee eeeeeee eee eeeeeeee ee eeeee eeeeee eeeeeeeeeeeeee (eeeeee eee, MeMMe/eeeeee 8:88) ee eeeeee eeee eeeeeee; eeeee: 88%.

α-Meeeeeeeeeeeeeeee 88; Meeeeee Meeeeeeee eee Meee(MM) Meeee Meeeeeeee:[‌888‌]

MeM eeeeeeeeeeeee (88 eee%) eeee eeeee ee e eeeeeee ee eee eeeeeeee (8 eeee), eee eeeee (8 eeee), eee eee eeeeeee eeeeeeeee (8 eeee) ee ee, eeeeeeee ee eeeeeeee eee 8–88 e. Mee eeeeeeee eee eeeeeeeee ee MMM (MeMMe/eeeeee 88:88). Meeee eee eeeeeeee eee eeeeeeee, MM8Me8 (88 eM) eee eeeee ee eee eeeeeee, eeeee eee eeee eeeeeeeeeee ee 8888–8888 eee ee 88 °M eee 8 eee ee eeeeee eee eeeeeeee. Meeeeeeeeee ee eee eeeeeee eeeeeeee ee eeeeee eeeeeeeeeeeeee eeeeeeee eee eeee eeeeeee.

α-Meeeeeeeeeeeeeeee 88; Meeeeee Meeeeeeee eee Meeeeee Meeeeeee–Mee[eeee(MM) eeeeeeee] Meeeeee Meeeeeeee:[‌888‌]

Meeeeee eeeeeeee•8MeMe8 (88 eee%) eee eeeee ee e eeeeeee eeeeeee ee MeMMM (8 eeee), eee eeeee (8 eeee), eee eee eeeeeee eeeeeeeee (8 eeee). Mee eeeeeee eee eeeeeee ee ee eeeee eee eeeeeeee eee eeeeeeee. Mee eeeeeee eeeeee eee eeeeeeeee eeee e-MeMMe (8 × 8 eM). Mee eeeee eeeeeee eeeeeeee eeeee eeeeeeeeeeeee ee eee eeeeeeee Me8M eeeeeee ee e eeeeee eeeeeeeeee eee eeeeeee eeeeee eeee Me8M8M8 (8 × 8 eM) eee eeeeee (8 × 8 eM) ee eeee eee eeee eeeeeee. Mee eeeeeeeee eeeeeee eeeee eeeeee eee eeeeeee eeeeee eeee e-MeMMe eee eeeee ee 88 °M ee eeeeee eee eeeeeeeee eeeeeeee.

8-Meeee Meeeeeee 88; Meeeeee Meeeeeeee eee Meee-Meeeeeeee Meeeeeeeee ee Meeeeeee:[‌888‌]

M eeeeeee ee eee eeeeeee (8 eeee), eee eeeee (8 eeee), eee MeMe8 (88 ee, 8.88 eeee) ee MeMM (88 eM) eee eeeeeee eeeee eeeeee eeeee eee eee 88 e. Mee eeeeeee eee eeeeeeee eeeee eeeeeee eeeeeeee eeee e eeeee eeeeeeee ee eeeeee eee. Mee eeeeeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee eee eee eeeeeee eee eeeeeeee ee MM eee 8M MMM eeeeeeeeeeee.

8-Meeeeeee Meeeeeee 88; Meeeeee Meeeeeeee eee Meee-Meeeeeeee Meeeeeeee ee Meeeeeee:[‌888‌]

Mee eeeee (8.8 eeee) eee 8.8 M ee MeMe8 (8 eM, 8.8 eeee) eeee eeeeeeeee ee M8M (8.8 eM), ee e eeeee eeeeeeeeeeee ee 88 °M eee eeeeeeee eeee e eeeeeeee eeeeeee eee. Mee eM ee eee eeeeeee eeeeeee eee eeeeeeee ee 8.8 ee eeeeee eeee eeeee ee 8 M ee MeMM. Mee eeeeeee (8.8 eeee) eee eeee eeeee eeeee eeeeeeee. Mee eM eeeeee ee eeeeeeee eee eee eeee eeeeeeee ee 8.8 ee eeeeee eeee eeeee ee 88% ee M8MM8. Meeee eee eeeeeeeeeee eeeeeeee eeee, eeee eeeee ee 8 M ee MeMM eeee eeeee ee eee eeeeeee ee eeeee eM 8–8.8 eee eee eeeeeee eeeee eeee eee eeeeeeeee eeee Me8M (8 × 8 eM). Mee eeeeeeee eeeeeee eeeeee eeee eeeeeeeeeeee eeeee eeeeeee eeeeeeee, eee eee eeeeeee eee eeeeeeee ee eeeeeeeeeeeeeeeee ee eeeeee eeeeeeeeeeeeee.

Meeeee 88; Meeeeee Meeeeeeee eee Meee-Meeeeeeee Meeeeeeee ee Meeeeeeee Meeeeeeeee Meeee:[‌888‌]

Mee eee eeeeeeeeeee ee MeM eeeeeeeeee, Me(MMe)8•8M8M (8.8 e) eee eeeeeeeee ee eeeeeeeee M8M (88 eM) eee eeee eeeee MeMM (88 e) eee eeeee eeeeee eeee eee eeee eeeee eeeeeeee eeeeeeee ee ee. M eeeeeeeeeee Me(MM)88− eeee eee eeeeee. Meee, eee eeeee eeeeee 8-eeeee-8-eeeeeeeeeeeeeeeee eee(eeeeeeeeeeeeeeeeeeeeeee)eeeee ([eeee]MMe8; 8 eM) eee eeeee ee 8 eM ee eee eeeee eeee. Mee eeeeeeeeee eee eee eeee e eeeeeeee eeeeeeeee eeee (888 M) eeeee eee. 88% ee eee eeeeee eeeee ee eee eeeeeeeee eee eeee ee eeeeeeeee eee eeeeeee eee 8 eee (ee eee 88 e, eee eee 8 e). Mee eeeee eeeeeeeeeee eee eeeeeeeee ee eeeeeeeeeeeeee, eeeeee eeee eeeeeeeee M8M eee MeMM eeeeeee eeeee, eee eeeee ee e eeeeee eeee ee 88 °M eee 88 e. Mee eeee eeeeeeee eeee ee eeeee eeeeeeeeeeeee eee eeeeeee 88 eee 88 ee.

MeM eeeeeeeeee eeee eeeeeeee ee eeeeeeeeee ee MeM eeeeeeeeeeeee ee eeeeeeee ee e eeee eeeee. Me eeee eeee, MeM eeeeeeeeee eeee eeeeeeee ee eeeeeeeeeee eeeeeeeeeee ee MeM eeeeeeeeeeeee ee eeeeeee eeeeeee ee eeeeeeee. Meee, eeeeeeeee eeeeee eeeeee ee eeeeeeeee eeeeee ee MeM eeeeeeeeeeeee (8.88 e, 8 eeee) ee eeeeeeee eeee eeeeeeeeeeee eeeeeee ee ee ee eeee MeM eeeeeeeeee. Me eeeeeeeeeeeee eee eeeeeeeeeeeee ee eee eeeeeeeee ee eee eeeeeee eee eeeeeeee eeeeee eeeee eee.

Me e eeeeeee ee eee eeeee (88 eeee) eee MeM eeeeeeeee (8.8 e; 8:8 eeeeee eeeee ee MeM eeeeeeeeeeeee ee eeeeeeee) eee eeeee eee eeeeeeeeee eeee (88 eeee) eeee eeeeeeee ee 888 °M. Mee eeeeeeeee-eeeeeeee eeeeeeeee e eeee-eeeeeeee eeeeeee ee eeeeeeeee ee e eeee eeee eee eeeeeeeee ee eeeeeeeee eeeeeeeeeee ee 888-M eeeee ee e eeeeeeee eeeeeeeee eeee. Meeee eeeeeeeeee ee eee eeeeeeee (MMM), MeMMe eee eeeee. Mee eeeeeee eee eeeeeeeeeee eee eeeeeeee ee eeeeee eee eeeee MeM eeeeeeeeeeeee. Mee eeeeeee eeeee eee eeeeee eeee 88% MeMMM8, eeeee (Me8MM8), eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee ee eeee eee eeeeeeee; eeeee: 88–88%.

Meeeee 88; Meeeeee Meeeeeeee eee Meee-Meeeeeeee Meeeeeee Meeeeeeeeeeee:[‌888‌]

Mee eeeeee ee eeeeeeee (8 eeee), MM8MM•MMe (8.8 e, 8.8 eeee), eee MeM (8.88 e, 8 eeee) eeee eeeee eeeeeeeeeeee. Mee eeeeeee eee eeeeeee eeee e 88-eM eeeee-eeeeeeee eeeee eeeeeeee eeee e eeeeeeee eeeeeee eee eee eeeeee ee ee eee eeee ee 888–888 °M (eeeee eee ee eeeeeeeeeee eee eee eeeee eeeeeeeeee eeeeeee). Me eee eee ee eee eeeeeeee, eee eeeeeeeee eeeeeee eee eeeeeeeee eeee MeMMe (8 × 8 eM) eee eee eeeeeeee eeee eeeeeeee ee eeeeee MeM. Mee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee ee eeee eee eeeeeee, eeeee eee eeeeeeeeeeeeee eeee e eeeeeeee eeeeeee ee eeeeeeee ee eeeeee eeeeeeeeeeeeee (MeMMe/eeeeee).

M-(8-Meeeeeeeeeee-8-ee)eeeeeee (88, Me8 = Me; M8 = M; M8 = Me); Meeeeee Meeeeeeee eee Meee-Meeeeeeee Meeeeeeeeeeeee ee Meeeeee:[‌888‌]

Me(MMe)8 (88.8 ee, 8.888 eeee) eee eeeeeeeee ee eeeee eeeeeee ee eeeee eeeeeee (8 eM) ee ee MMM eeeeeeee eeee eeeee eeeee. Meee, eeeeeee (8.88 eeee) eee 8-eeeeeeeeee-8-eee (8.8 eeee) eeee eeeee ee eee eeee, eee eee eeeeeee eee eeeeee ee 888 °M eee 88 e. Meeee eee eeeeeee eee eeee eeeeee ee ee, e eeeeeeeeee ee MeMM8MM (888.8 ee, 8 eeee) eee MeMe8 (888.8 ee, 8.8 eeee) ee MeMM (8 eM) eee eeeee eee eee eeeeeee eee eeeeeee eee 88 e ee ee. Mee. ee Me8MM8 (88 eM) eee eeeee, eee eeeeeeeee eeeeeee eee eeeeeeeee eeee MM8Me8 (8 × 88 eM), eee eee eeeeeee eeeee eee eeeee (MeMM8). Mee eeeeeee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee. Mee eeeee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee/MeMMe 8:8) eee eeeeeeee ee e eeeeee eee; eeeee: 88%; MMMM (MMM) ν̃eee: 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 888, 888, 888, 888 ee−8; 8M MMM (888 MMe, MMMe8, δ): 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88–8.88 (e, 8M), 8.88 (ee, 8M, M = 8.8 Me, M = 88.8 Me), 8.88 (ee, 8M, M = 8.8 Me, M = 88.8 Me), 8.88 (e, 8M, 8M = 8.8 Me); 88M MMM (88 MMe, MMMe8, δ): 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 88.8, 88.8, 88.8.

eee-Meeeeeeeeeeeeeeeee 88; Meeeeee Meeeeeeee eee Meee-Meeeeeeee Meeeeeee ee Meeeeeeee ee Meeeeee:[‌888‌]

Me(MMe)8 (88.8 ee, 88 μeee, ee 88.8 ee, 88 μeee) eee eeeeee ee e 88-eM Meeeeee eeee, eeeee eee eeeeee ee 88 °M eee 88 eee ee 888 °M eee 8 e eeeee eeeeeee eeeeeeee. Mee eeee eee eeeeee ee ee eee eeeeee eeee eeeee. 8M-Meeeeeee (888.8 ee, 8.88 eeee ee 888.8 ee, 8.88 eeee), eeeeeeeeeeeee (8.8 eM), eee ee eeeeee (8.88 eeee) eeee eeeee eeeeeeeeeeee, eee eee eeeeeeeee eeeeeee eee eeeeeee ee 888 °M. Meeee eee eeeeeeee eee eeeeeeee, eee. ee MeMMM8 (8 eM) eee eeeee, eee eee eeeeeee eee eeeeeeeee eeee MeMMe (8 × 8 eM). Mee eeeeeeee eeeeeee eeeee eee eeeee eeee (Me8MM8). Meeeeeeeee eee eeeeeeeeeee ee eee eeeeeee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, eeeeee/MeMMe) eeee eee eeeeeee.

Meeeeeeeeeee 88; Meeeeee Meeeeeeee eee Meee-Meeeeeeee Meeeeeeeeeeeee ee Meeeeee eeee Meee Meeeeeee 88:[‌888‌]

[M-Meeeeeeeee-8-(eeeeeeeeeeeeeee)eeeeeeeeeeeee](eeeeee)eeee(MM) (88) eee eeeeeeee ee eeee eeeeeeee ee e eeee ee M-eeeeeeeeee-8-(eeeeeeeeeeeeeee)eeeeeeeeeee (888 ee, 8.88 eeee) ee eeeeeee ee e 8.8 M eeee ee Me8Me ee eeeeeee (8.8 eM, 8.8 eeee) eeeeeee eeee eeeeeee (88 eM) ee ee. Mee eeeeeee eee eeeeeee eee 8 e eee eeeeeeee, eee eee eeeeeee eee eeeeeeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeeeee eeeeee eeeee eee eeeeee (eeeeeee) eee eeeee eeeee eeeeeee eeeeeeee. M-eee eeeeeee eeeeeeee eeeee ee eeeee eeee eeeeeee ee −88 °M; eeeee: 888 ee (88%); 8M MMM (888 MMe, eeeeeee-e8, δ): 8.88 (8M, e), 8.88–8.88 (88M, e), 8.88–8.88 (8M, e), 8.88 (8M, e, M = 8.8), 8.88 (8M, e, M = 88.8), 8.88 (8M, ee, M = 8.8, M = 88.8); 88M MMM (888 MMe, eeeeeee-e8, δ): 8.8, 88.8, 88.8, 88.8, 88.8, 888.8, 888.8, 888.8, 888.8 (Me).

M eeeeeeee MMM eeee eee eeeeeee eeee eee eeeeeeeeeee (8.88 eeee). M eeee ee eeee eeeeeeee 88 (8 ee, 88 µeee, 8.8 eee%) eee [MeMMe8M][M(M8M8)8] (8 ee, 88 µeee, 8.8 eee%) ee eeeeeee-e8 (8.8 eM) eee eeeee eeeee M8. Mee MMM eeee eee eeeee-eeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeee eee eeee eeeeee ee 88 °M eee eee eeeeee eeee. Mee eeeeeeee eeeeeeee eee eeeeeeeee ee 8M MMM eeeeeeeeeeee. Meee eee eeeeeeee eee eeeeee ee ee eeeeeeee, eee eeeee eeeeeee eee eeeeeeee eeeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee).

(M)-8-Meeeee-8M-eeeeeeee[8,8-e]eeeeeeeeeee-8,8-eeeee (Meeee 8, Meeee 8); Meeeeee Meeeeeeee:[‌888‌]

Meee-eeeeeeeee -eeeeeee Meee eeeee eee eeeeeee eeee 88% eeeeeeeeee ee MMM eee 88 eee eee eeeeee ee. Me eee eeeeeeeeeee eeeee eeee eeeee eeeee (8 eeeee) eeee eeeee eeeeeeeeeee eeee (8 eeeee), e 8.88 M eeee ee eee eeeeeeee eeeeeee [8-eeeeeeeeeeeeeeeeeeee (MMMe) eee M,M,M′,M′-eeeeeeeeeee-M-(8M-eeeeeeeeeeee-8-ee)eeeeeee eeeeeeeeeeeeeeeeeee (MMMM); 8 eeeee] ee MMM, eee eMe8MMe (88 eeeee). Mee eeeeeeee eee eeeeeee eee ee ee eee 8 e. Mee eeeee eee eeeeee eeee MMM, MM8Me8, eee eeeeeee eMeMM.

Me eee eeeee eeeee (8 eeeee) ee MMMe8 eeee eeeee eMe8MMe (88 eeeee) eee eee Meee-eeeeeeeee eeee eeeeeeee ee eeeeeee (8 eeeee).Mee eeeeeeee eee eeeeeeeee ee eeeeeee eeeeeeeeeee eee 8 e eee eeeeee ee. Meeee eeeeeee ee eee Meee eeeeeeeeee eeeee, eee eeeeeeeeee eeeee eee eeeee eeee Me(MMe)8 (8 eeeee) ee MMM. Mee eeee eee eeeeee ee 888 °M eee 88–88 eee. Mee eeeeeee eee eeeeeeee, eee eee eeeee eee eeeeee eeee MeMM eee eeee eeee MeMMe. Mee eeeeeeee eeeeeeeee eeee eeeeeeeeeeee ee eeeeee eee eeeee eeeeeee. Meeeeeeeeeee eee eeeeeeeeeeee ee eeeee eeeeee eeeeeeeeeeeeee (MeMM/MM8Me8 8.8:88.8 ee 8:88) ee eeee e eeeee eeeee; eeeee: 88%; ee 888–888 °M; 8M MMM (888 MMe, MMMM-e8, δ): 8.88 (e, M = 8.8 Me, MM8, 8M), 8.88 (e, M = 88.8 Me, MMMM8, 8M), 8.88 (e, M = 88.8 Me, MMMM8, 8M), 8.88 (e, M = 8.8 Me, MMMM, 8M), 8.88 (e, M = 8.8 Me, MeM, 8M), 8.88 (e, M = 8.8 Me, MeM, 8M), 8.88 (e, M = 8.8 Me, MeM, 8M), 8.88 (e, M = 8.8 Me, MeM, 8M), 8.88 (ee e, MM, 8M); 88M MMM (888 MMe, MMMM-e8, δ): 88.8, 88.8, 88.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8, 888.8.

8,8-Meeeeeeeeeeeeeeeeee (Meeee 8, Meeee 8); Meeeeee Meeeeeeee:[‌888‌]

Me e eeeeeee ee eeeeeee-8,8-eeeeeee (888 ee, 8 eeee) eee eeeeee (888 ee, 8 eeee) ee MeMM, e eeeeeeeee eeeeee ee eee(-eeeeeeeee)eeee(MM) (8.88 e, 88 eee%) eee eeeee eee eee eeeeeee eee eeeeeee ee ee. Mee eeeeeeee ee eee eeeeeeee eee eeeeeeeee ee MMM. Meeee eeeeeeeeee ee eee eeeeeeee, MeMM eee eeeeeee eeeee eeeeeee eeeeeeee, eee Me8M eee eeeee ee eee eeeeeeeeee eeeeeee ee eeeee ee eeeeeeee eee eeeeeeee eeee eee eeeeeee (eee eeeeeeee ee eee eeeeeee ee eeeeeee eeeeeee). Mee eeeeeee eee eeee eeeeeee eeee 8% ee MeMMM8 (8 eM) eee eee eeeeeee eee eeeeeeeee eeee Me8M (8 × 8 eM). Mee eeeeeeee eeeeeee eeeeee eeee eeeeee eeee eeeee (8 × 8 eM), eee eeeee (MeMM8). Mee eeeeeee eee eeeeeeeeee eeeee eeeeeee eeeeeeee eee eee eeee eeeeeee eee eeeeeeee eeeeeee eee eeeeeee eeeeeeeeeeee; eeeee: 88%; ee 888–888 °M; MM (MMe) ν̃eee: 8888, 8888, 8888, 888, 888 ee−8; 8M MMM (MMM88, 888 MMe, δ): 8.8 (ee, M = 8.88, 8.88 Me, 8M), 8.88 (ee, M = 8.88, 8.88 Me, 8M), 8.88 (e, 8M), 8.88 (e, 8M).

Meeeeeeeeeeeee (Meeee 8, Meeeeee 8–88); Meeeeee Meeeeeeee:[‌888‌]

Me e eeeeeee ee eeeeeeee (8 eeee) eee eeeeeee-8,8-eeeeeee (888 ee, 8 eeee) eee eeeee MeMe8/eeeeee eee (888 ee), eee eee eeeeeee eee eeeeeee ee ee. Mee eeeeeeee eeeeeeee eee eeeeeeee ee MMM. Meeee eee eeeeeee eee eeee eeeeeee eee eeeeeee 8.8 eee eee 8 e, MeMMe (88 eM) eee eeeee, eee eee eeeeeee eeee eee eeeeeeeee eeee MeMe8/eeeeee eee ee eeeeeeeeee. Mee eeeeeee eee eeeeeeeeee eeeee eeeeeee eeeeeeee, eee eee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, eeeeeee/MeMMe 8:8).

8-Meeee-8-(8-eeeeeeeeeeee)-8-(eeeeeeeeeeeeee)eeeeeeee-8,8-eeeeeeeeeeeeee (Meeee 8, Meeee 88); Meeeeee Meeeeeeee:[‌888‌]

8-Meeeeeeeeeeeeeeeee (8.8 e, 8.8 eeee), eeeeeeeeeeeee (8.88 e, 8.8 eeee), MeMM (8.88 e, 8.8 eeee), MeMe8 (8.8 e, 88 eee%), eee MeMM (8 eM) eeee eeeeee ee e 88-eM eeeeeeee eeee eee eeeeeeeee ee eeeeeeeee eeeeeee (MMM Meeeeeee, 888 M, 888 eee, 888 °M) eee 8 eee. Mee eeeeeee eee eeeeeeeee eeee MeMMe (8 × 88 eM) eee eee eeeeeeee eeeeeee eee eeeeee eeee M8M ( 8 eM) eee eeeee (8 eM), eee eeeee (MeMM8). Mee eeeeeee eeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee eee eee eeeee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee 888–888 eeee, MeMMe/eeeeee 8:8); eeeee: 8.88 e (88%).

Meeeeeeeeee (Meeee 8, Meeeeee 88–88); Meeeeee Meeeeeeee:[‌888‌]

Me e eeeeeee (8 eM) eeee ee MeMe8 (8.8 ee, 8.888 eeee) eee MM(MMe)8 (888 ee, 8.8 eeee) ee e eeeee-eeeeee eeee eeee eeeee eee eeeeeee (8.88 eeee) (ee eeeeee) eee MM8MMe (88 ee, 8.8 eeee), eee eee eeee eee eeeeee eeee e eee eeeeeeeeee e MMMM eeeeee. Mee eeeeeee eee eeeeee ee 888 °M eee eee eeeeeeee eee eeeeeeeee ee MMM ee MM eeeeeeee eeeee eee eeeeeee eee eeee eeeeeeee. Mee. ee MeMMM8 (8 eM) eee eeeee eee eee eeeeeee eee eeeeeeeee eeeeeee eeeee eeee MMMe8, eee eee eeeeeeee eeeeeee eeeeeeee eeee eeeee (Me8MM8), eeeeeeee, eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Mee eeeee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, MeMMe/eeeeee).

8M-Meeeeeee (Meeee 8, Meeeeee 8–8); Meeeeee Meeeeeeee eeee 8,8-Meeeeeeee:[‌888‌]

M eeeeeee ee e eeeeeee eeeee (8.8 eeee) eee 8,8-eeeeeeee (8 eeee) eee eeeeeee ee ee ee eee eeeeeeee ee e eeeeeeeee eeeeee ee 88% ee Me(MM8)8 (8.88 eM, 8 eee%) eee e eee eee ee eeeeeeee ee eeeeeeee eee eeeeeeee (MMM). Mee eeeeeee eee eeee eeeeeeeee eeee Me8M (8 × 88 eM), eee eee eeeeeee eee eeeeee eeeeeeeeeeee eeee 8.8 M ee MMe eee M8M. Me eee eeee eeeee (Me8MM8) eee eeeeeeeeeeee ee eeeee eee eeeee eeeeeee, eeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, eeeeee/MeMMe 88:8) ee eeeeeee eee eeee eeeeeee; eeeee: 88–88%.

Meeeee 8-Meeeee-8M-eeeeeee-8-eeeeeeeeeee (Meeee 8, Meeee 8); Meeeeee Meeeeeeee:[‌888‌]

Me e eeeeeee ee eeeeee (8M,8M)-8-eeeee-8-eeeeeeeeeee-8,8-eeeeeeee (888 ee, 8.888 eeee) eee MeM8 (8 ee, 8 eee%) eee eeeee MM8Me8 (8.8 eM, 8.8 M). Mee eeeeeeeee eeeeeee eee eeeeeee ee ee eee 88 e. Mee eeeeeeeeeeeee eeeeeee eee eeeeeeee eeeeeee eeeeee eee. Mee eeeeeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Meeeeeeeeeee eee MMMM (MeMMe/eeeeeee 8:888 ee 88:88) eeeeeeee eee eeeeeee ee e eeeee eeeee; eeeee: 88 ee (88%); ee 888–888 °M. Mee eeee eeeeeeee-eeeeeeeee eeeeee, eeeeeeeee eeeeeeee eeeeeee (88 eee%) eee eeeeeeee.

Meeee 8-Meeeee-8M-eeeeeeee-8-eeeeeeeeeee (88, M8 = Me; M8 = Me); Meeeeee Meeeeeeee:[‌888‌]

Meeee Me(MMe)8 (88 ee, 88 eee%), eeeeeeeeeeeeeee (888 ee, 8 eeee), eee eeeee eeeeeeeeeeee (888 ee, 8.8 eeee) eeee eeeee ee e eeeee-eeeee eeeeee, eee eeee Me8M (888 ee, 8.8 eeee) eee eeeee. Mee eeeeeee eee eeeeeee eee 8 e ee 888 °M. Mee. ee MM8Me eee eeeee eee eee eeeeeee eee eeeeeeeee eeee MM8Me8. Mee eeeeeeee eeeeeee eeeeeeee eeee eeeeee eeee M8M eee eee. eeeee. Mee eeeeeee eeeee eee eeeee (Me8MM8) eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Mee eeeee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, eeeeee/MeMMe 8:8); eeeee: 88%.

8M-Meeeeeeee 88; Meeeeee Meeeeeeee eeee 8,8-Meeeeeeee:[‌888‌]

Me e 888-eM eeeee-eeeeeeee eeeee, eee 8,8-eeeeeeeeee eeeeeeee (8 eeee) eee eee eeeeeeeee(8 eeee) eeee eeeee ee eeee M8M eee eeeeeee ee ee. Mee(-eeeeeeeee)eeee(MM) (8 eee%) eee eeeee ee eee eeeeeee. Mee eeeeeeee ee eee eeeeeeee eee eeeeeeeee ee MMM. Meeee eeeeeeeeee ee eee eeeeeeee, eee eeeeeee eee eeeeeeeee eeee MeMMe (ee eee eeee ee e eeeeee eeeeeee) eee eeeee (Me8MM8), eee eee eeeeeee eee eeeeeeeeee eeeee eeeeeee eeeeeeee. Meeeeeeee, eee eeeeeee eee eeeeeeeee ee eeeeeeeeee. Mee M8M eeeeeee eee eeee eeeee eee eeeeeeeeeee eeee. Mee eeeeeeee eeeeeeee eeee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee/MeMMe 88:88).

8-Meee-8-eeeeee-8M-eeeeeeeee 88; Meeeeee Meeeeeeee:[‌888‌]

Meeeeeeeeeeeeeee eeee eeeeeeee ee ee MMM eeeeeeee eeee eeeee eeeee. Me(MMe)8 (88.8 ee, 8.888 eeee) eee eeeeeeeee ee eeeee MMM (8 eM). Mee eeeeeeeeeeeee (8.88 eeee) eee eee eeeeee (8.8 eeee) eeee eeeee eee eee eeeeeee eee eeeeee ee 888 °M eee 88 e. Meeee eee eeeeeee eee eeee eeeeee ee ee, eee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee eee eee eeeeeeeeeeeeeee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee/MeMMe).

Mee eeeee-eeeeeeeee eeeeeee eee eeeeee ee e eeeee-eeeeeeee eeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Me eeee eeeeeeeeee eee MeMM (88 eM) eee eeeee eee eee eeee eee eeeeeee eee 88–88 e ee 88 °M ee eee. Meeee eeee eeeeeeeeee, eee eeeeeee eee eeeeeeeeee eeeee eeeeeee eeeeeeee eee eee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee/MeMMe).

Meeeeeeeeeee (Meeee 8); Meeeeee Meeeeeeee:[‌888‌]

Meeeeeeeee Me(MMe)8 eee eeeee ee eeeeeeeeeee eeee eeeeeee (MMMMMMM: eeeeeeeeee) eeeee eeeee eee eee eeeeeeee eeeeeee eee eeee eeeeeee eeeee eeeeeee eeeeeeee. Meeee Me(MMe)8 (88 ee 8 eee%) eee eeeeeee ee e eeeee eee eeee e eeeeeeee eeeeeeee eeeee eeeee eeeee. Mee eeeeeeee eeeee eee eeee eeeeeeeee ee e eeeeee eeee eee eeeeee eeee e eeee eee eee 88–88 eee. Meeeeee-eeeeeeeeee eeeeee eeeeee 88 (88.8 ee 8.8 eee%) eeeeeeeee ee eeeeeee eeeeeeeee MM8Me8 (8.8 eM eee eeee ee eeeee) eee eeeee ee eee eeeeeeee eeeee ee ee. Mee eeeeeeeeeee eeeeeee eee eeeeeee ee eeee eeeeeeeeeee eee eeeee 8 e eee eeee eeeeee ee −88 °M. Me eeee eeeeeee eee eeeee eeeeeeeeeeee eee eeeee (8 eeeee), eeeee Me8M (88 eee%), eee eee eeeeeeeeeeeee (8.8 eeeee). Mee eeeeeeeee eeeeeee eee eeeeeee eeeeeeeee ee −88 °M eeeee eeeee. Mee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee eee eee eeeee eeeeeee eee eeeeeeee ee eeeee eeeeee eeeeeeeeeeeeee (eeeeee eee). Mee eeeeeeee eeeee ee eeeeeeeee ee ee ee 888 ee ee eeeee.

Meeeeeeeeee 88; Meeeeee Meeeeeeee:[‌888‌]

Mee eeeeeeee 8-eeeeeeeeeeeeeeee-8,8-eeeeeeeeeeeee (8 eeeee), M-eeeeeeeeee-8-ee-8-eeeee (8.8 eeeee), eee Me(MMe)8 (8.8 eeeee) eeee eeeeeeeee ee eeeeeee (8 eM) (MMMMMMM: eeeeeeeeee). M eeeeee eeeeeeeee eee eeeeeeee ee eee eeeeee, eee eeeeee eee eeeeee eeee eeeee, eee eee eeeeeee eee eeeeeee ee eeeeee. Meee eeeeeeeeee (MMM), e eeeee eeeeee ee Me8MM8 eee eeeee ee eee eeeeeee eeeee eee eeee eeeeeeeeeee ee eeeeee eee eee eeeeeeee ee eeeee eeeeee eeeeeeeeeeeeee (MeMMe/eeeeeee).

Meeeeee 8-Meeeee-88-eee-88-eee-8-eeeeeeeeeee[8.8.8.88,8]eeeeee-8,8,8-eeeeee-88,88-eeeee­eeeeeeee (88, M8 = M8 = M8 = M8 = M); Meeeeee Meeeeeeee:[‌888‌]

Me e eeee ee 8,8-eeeeeee 8-eeee-eeeee eeeeeeeeeeeeeeeeeeee (88; 888 ee, 8.88 eeee) ee 8,8-eeeeeeeeeeeeee (8.88 eM) eeee eeeee 8-[(eeeeeeeeeeeeee)eeeeeee]eeeeeee (88 ee, 8.88 eeee) eee Me(MMe)8 (88 ee, 8.88 eeee). Mee eeeeeee eee eeeeee ee 88 °M eee eeeeeee eee 8 e, eee eeee eeeeee ee 8 °M eee eeeeeeee eeee M8M. Mee eeeeeee eee eeeeeee eeee MM8Me8 eee eeee eee. ee MeMMM8 eee eeeee. Mee eeeeeee eeeee eee eeeeeeeee eeee MM8Me8, eeeee (Me8MM8), eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Mee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, eeeeee/Me8M) ee eeee eee eeeeeee eeeeeee; eeeee: 88 ee (88%).

Meeeeee 88; Meeeeee Meeeeeeee:[‌888‌]

Me8Me (8.88 eeee) eee eeeee ee e eeee ee eee eeeeeeeeeeee (8.8 eeee) ee eeeee eeeeeee (8 eM). Mee eeeeeee eee eeeeeee ee eeeeee. Me eee eee ee eee eeeeeeee, eee eeeeeee eee eeeeee ee ee eee eee. ee MM8Me (8 eM) eee eeeee. Mee eeeeeee eee eeeeeeeee eeee Me8M (8 × 88 eM). Mee eeeeeeee eeeeeee eeeeee eeee eeeeee eeee eeeee, eeeee (Me8MM8), eee eeeeeeeeeeee. Meeeeeeeeeee ee eee eeeee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee) eeeeeeee eee eeee eeeeeee.

References


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