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Please login or sign up for a free trial to access the full content. Carboalumination of Alkenes and Alkynes

DOI: 10.1055/sos-SD-107-00059

Oishi, M.; Takikawa, H.Science of Synthesis Knowledge Updates, (2010493.

As described in Section, the successful carboalumination of alkenes with tri­methylaluminum as well as ethyl or higher alkyl congeners has been realized with the assistance of bulky chiral zirconocene catalyst 1.[‌1‌] Both enantiomers of 1 can be obtained from the appropriate enantiomers of menthol with relative ease.

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M8 Meeeeeeeeeee M Meeee (8/8) Meeee (%) Mee
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Meeeeeee Meeee (8/8) Meeee (%) Mee
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(8M)-8-Meeeeeeee-8-eee (8); Meeeeee Meeeeeeee:[‌88‌]

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