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10.13.1.1.1.4.1.2.2 Variation 2: Closure in Water Alone

DOI: 10.1055/sos-SD-110-00001

Joule, J. A.Science of Synthesis Knowledge Updates, (20102121.

Microwave-assisted cycloisomerization of 2-alkynylanilines in water, without base, acid, or a metal catalyst, must surely be the simplest variation of this method; sundry 2-arylindoles can be prepared in moderate to acceptable yields in this way.[‌425‌]

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