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10.24 Pyrido[1,2-a]indoles and Azapyrido[1,2-a]indoles

DOI: 10.1055/sos-SD-110-01869

Harris, P. A.Science of Synthesis Knowledge Updates, (202131.

General Introduction

The synthesis and chemistry of pyrido[1,2-a]indoles 1 (Scheme 1) are reviewed as a subclass in Section 10.24.1. Since the published chemistry around the core pyrido[1,2-a]indole tricycle is limited, related systems with benzo-fused rings at the pyridine ring, namely indolo[1,2-a]quinolines 2, indolo[1,2-b]isoquinolines 3, indolo[2,1-a]isoquinolines 4, and indolo[1,2-f]phenanthridines 5, are covered in this subclass. Since they are grouped together, to avoid confusion, the numbering system used in the section titles to described the bonds formed will follow that for the core pyrido[1,2-a]indole (1) tricycle, as illustrated in Scheme 1.

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References


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