Navigation

0 Hits

  • Previous / Next

You are using Science Of Synthesis as a Guest. Please login or sign up for a free trial to access the full content.
11.17.6.1.3.2.2.2 From α-Functionalized Carbonitriles and Aminothiocarbonyl Compounds

DOI: 10.1055/sos-SD-111-00123

Koutentis, P. A.; Ioannidou, H. A.Science of Synthesis Knowledge Updates, (20101277.

2-Bromo-2-phenylacetonitrile reacts with 1-acetylthiourea in ethanol to give thiazole 31 in low yield (Scheme 14).[‌131‌]

Meeeee 88 Meeeeeee ee 8-Meeee-8-eeeeeeeeeeeeeeeeee eeee 8-Meeeeeeeeeeeee[‌888‌]

Meeeeeeeeeee Meeeeeeee

M-(8-Meeee-8-eeeeeeeeeeeee-8-ee)eeeeeeeee (88):[‌888‌]

8-Meeee-8-eeeeeeeeeeeeeeeeee (8.88 e, 8.88 eeee) ee MeMM (88 eM) eee eeeeeee eeee 8-eeeeeeeeeeeeee (888 ee, 8.88 eeee) ee ee eee 8 e, eee eeee eeeeee ee eeeeee eee 8.8 e. Mee eeeeee eeeeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee eee eeee eeeeeeeeeee eeeeeee MM8Me8 eee eee. ee MeMMM8. Mee eeeeeee eeeee eee eeeeee eeee eeeee, eeeee (Me8MM8), eeeeeeee, eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee. Meeee eeeeeeeeeeeeee (eeeeee eee, MeMMe/eeeeeee) eeee eee eeeeeee; eeeee: 888 ee (88%).

References