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17.4.1.5.2.4 By Valence Isomerization of Benzene Oxide

DOI: 10.1055/sos-SD-117-00028

Hong, J.Science of Synthesis Knowledge Updates, (20121265.

Fungal monooxygenase catalyzed aromatic hydroxylation of methyl benzoate-2,6-d2 (11) provides an equilibrium mixture of the labeled benzene oxide 12 and oxepincarboxylate derivative 13 in 65% yield (Scheme 5).[‌6‌]

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