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DOI: 10.1055/sos-SD-120-00214

Sawamura, M.; Shimizu, Y.Science of Synthesis Knowledge Updatesearly view.

General Introduction

This is a further update to Science of Synthesis Section on the synthesis of carboxylic acids with retention of the functional group.[‌1‌‌3‌] In particular, this review focuses on asymmetric reactions and catalytic reactions, along with practical stoichiometric reactions, reported in the period 2010–2022. Note that although the focus is on transformations of alkanoic acids, some examples of the functionalization and reactions of benzoic acid substrates are also included.