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DOI: 10.1055/sos-SD-122-00004

Li, X.; Song, Q.Science of Synthesis Knowledge Updates, (20241316.

In 2005, Katritzky and co-workers developed two kinds of benzotriazole reagent for the synthesis of thiocarboxylic O-acid esters. The two benzotriazole reagents 8 and 10 are readily synthesized from Grignard reagents and acyl chlorides, respectively. Treatment of the benzotriazole reagents with appropriate alcohols forms the corresponding thionoesters 9 and 11 with high efficiency (Scheme 4).[‌5‌]

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