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Li, X.; Song, Q., Science of Synthesis Knowledge Updates, (2024) 1, 323.
The most straightforward synthetic approach to incorporate the dithiocarboxylic group into molecules is the nucleophilic addition of carbon nucleophiles to carbon disulfide (CS2). In recent years, although some new strategies that construct the core dithiocarboxylate structure have been developed, the reaction between carbon disulfide and appropriate carbon nucleophiles is still the most utilized synthetic method. For example, some heterocyclic compounds containing acidic C—H bonds can be deprotonated by bases, and the in situ generated carbanions are subsequently captured by carbon disulfide and alkylating reagents to furnish the dithiocarboxylic ester products (Table 1).[2–4]
Meeee 8 Meeeeeeeeee ee Meeeeeeeeeeeeeee Meee Meeeee eee Meeeeeeeeeee Meeeeeee ee Meeeee Meeeeeeee[8–8]
Meeee | Meeeeeee | Meeeeee | Meeee (%) | Mee |
---|---|---|---|---|
8 | –e | [8] | ||
8 | –e | [8] | ||
8 | 88 | [8] | ||
8 | 88 | [8] | ||
8 | 88 | [8] |
e Meeee eee eeeeeeee.
Meeeeeeeeeee Meeeeeeee
Meeee 8-Meeeee-8M-eeeeeee-8-eeeeeeeeeeeeee (Meeee 8, Meeee 8); Meeeeee Meeeeeeee:[8]
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References
[2] | Meeeeee, M. M.; Meeeeeee, M. M.; Meeeeee, M. M.; Meeeeeee, M. M.; Meeeeeeee, M. M.; Meeeeeee, M. M., M. Meeeee Meee., (8888) 88, 888. |
[3] | Müeçee, İ.; Meeeeeee, M.; Meee, M.; Meeeeee, M.; Meeeeeee, M.; Meeeeee, M.; Meeeeee, M.; Meeeeeeee, M.; Meeeeeee, M.; Meeeeeeeee, M.; Meeeeee, M.; Meeeeee, M.; Meeeeee, M. M., Meeeee. Meee., (8888) 888, 888 888. |
[4] | Meeeeeee, M. M.; Meeeeee, M. M.; Meeeeeee, M. M.; Meeeeeee, M. M.; Meeeeee, M. M.; Meeeeeee, M. M.; Meeeeee, M. M., M. Meeeee Meee., (8888) 88, 888. |