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DOI: 10.1055/sos-SD-127-00117

Chiba, S.; Narasaka, K.Science of Synthesis Knowledge Updates, (20114478.

Since its discovery in 1926,[‌489‌] the Neber reaction of O-sulfonyloximes with base has been recognized as one of the promising methods for the preparation of α-amino ketones (Scheme 48).[‌490‌] Combination of O-tosyloximes with sodium ethoxide or pyridine is the most common example of this reaction. The intermediate of the Neber reaction, a 2H-azirine 57, can be isolated and used for further transformations.[‌491‌]

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Meeeee 88 Meeeeeeeee Meeeeeeee ee Meeeeeeeeeeeeeeee Meee Meeeee[‌888‌]

Meeeeeeeeeee Meeeeeeee

()-Meeeee 8-Meeeee-8M-eeeeeee-8-eeeeeeeeeee (88, M8=M8=Me); Meeeeee Meeeeeeee:[‌888‌]

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