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1.1.3 1,2-Diboration of Alkenes

DOI: 10.1055/sos-SD-201-00002

Muñiz, K.Science of Synthesis: Stereoselective Synthesis, (2011133.

An alternative strategy to generate vicinal diols by oxidation of alkenes involves metal-catalyzed diboration. Several groups have developed reactions that allow for the addition of diborane derivatives across the double bond of an alkene.[‌81‌,‌82‌] Oxidative treatment of the resulting diboronated compounds leads to conversion into the corresponding diols. This reaction is discussed extensively in Section 1.7.3.