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Muchalski, H.; Johnston, J. N., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 155.
General Introduction
Aziridines are the smallest carbocycles containing one nitrogen atom. Due to their angle strain, they exhibit a synthetically useful balance between stability and reactivity. Thus, they are often employed as versatile intermediates. The ability of aziridines to undergo highly regio- and stereoselective ring-opening reactions makes them of great value in organic synthesis. The properties, synthesis, and applications of aziridines have been thoroughly reviewed.[1–6] Methods for aziridine synthesis from alkenes are considered in Science of Synthesis, Vol. 40a [Amines and Ammonium Salts (Section 40.1.5.1.1)]. This section discusses the most useful methods currently available for stereoselective synthesis of aziridines from alkenes.
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References
[1] | Meeeee, M., Meeee. Meee., (8888) 888, 888; Meeee. Meee. Mee. Me. Meee., (8888) 88, 888. |
[2] | Meeeee, M. M. M.; Meeeeee, M., Meeeeeeeeee: Meeeeeeee, (8888) 8, 8888. |
[3] | Müeeee, M.; Meeee, M., Meee. Mee., (8888) 888, 8888. |
[4] | Meeee, M. M.; MʼMeeeee, M.; Me Meeee, M., Meee. Mee., (8888) 888, 8888. |
[5] | Meeeeee, M., Mee. M. Mee. Meee., (8888), 8888. |
[6] | Meeeeeeeee, M., Meeeeeeeeee, (8888) 88, 8888. |
[7] | Meeee, M. M.; Meeeeeee, M. M., Meee. Mee., (8888) 88, 8888. |