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1.5.1 Reduction of Didehydroamino Acid Derivatives

DOI: 10.1055/sos-SD-201-00087

Ager, D.Science of Synthesis: Stereoselective Synthesis, (20111192.

Asymmetric hydrogenation reactions were first developed for the preparation of α-amino acid derivatives by the reduction of the corresponding acylated didehydroamino substrates. Further refinement has led to the possibility of other functionality being present in the substrate.


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