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1.2.1.1.1 Ketones with an Attached Chiral Moiety

DOI: 10.1055/sos-SD-204-00417

Wong, O. A.; Ramirez, T. A.; Shi, Y.Science of Synthesis: Asymmetric Organocatalysis, (20121784.

Selected examples of ketones 38 with an attached chiral moiety are listed in Scheme 2. Ketones 3, 4, and 5 are among the earliest chiral ketones investigated for asymmetric epoxidation.[‌27‌,‌28‌] Products 10 with up to 40% ee are obtained from the alkene substrates 9 examined.

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