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7.2.5 Conclusions and Perspectives

DOI: 10.1055/sos-SD-206-00590

Mori, Y.; Kobayashi, S.Science of Synthesis: Water in Organic Synthesis, (20121849.

Due to environmental concerns, green processes will become more and more important in industry. The use of water as a solvent is one of the most important methods to avoid the use of harmful organic solvents and develop green chemical process. At present, the use of water as a solvent in the chemical and pharmaceutical industries is still uncommon, and many of the examples are enzymatic systems, which are known to work in biological systems containing water. Modification of enzyme structure is a key technology, and thus various genetically engineered enzymes have been developed. For synthetic catalysts, aqueous transition-metal catalysts have also been utilized in industry, and these traditional aqueous catalysts are currently major players in organic reactions in water.

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