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1.1.4.2.3.3.3 (Alkoxymethyl)trifluoroborates

DOI: 10.1055/sos-SD-207-00131

Sandrock, D. L.Science of Synthesis: Cross Coupling and Heck-Type Reactions, (20131341.

The preparation of potassium (alkoxymethyl)trifluoroborates and their cross coupling with aryl and hetaryl halides can be performed to install alkoxymethyl groups on the arenes or hetarenes, giving (alkoxymethyl)arenes 25.[‌35‌] Using palladium(II) acetate and RuPhos, a variety of substrates have been utilized in this context (Scheme 18).

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