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1.2.1.4 Conclusions

DOI: 10.1055/sos-SD-207-00196

Denmark, S.; Chang, W.-T. T.Science of Synthesis: Cross Coupling and Heck-Type Reactions, (20131426.

A diverse range of silyl moieties has been successfully exploited for the cross-coupling reactions of aryl donors and a large number of methods exist that allow the coupling of aryl electrophiles in good yields. Other electrophiles such as alkenyl, allyl, benzyl, and alkyl substrates have also been explored, but many of these research areas require further investigation to improve scope and practicality. As a guide to practitioners, five types of silicon-based reagents that deserve some final comments are summarized below.

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