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1.3.1 Organotin Cross-Coupling Reactions

DOI: 10.1055/sos-SD-207-00327

Pitaval, A.; Echavarren, A. M.Science of Synthesis: Cross Coupling and Heck-Type Reactions, (20131527.

General Introduction

The Stille reaction of organostannanes with organic electrophiles is one of the most general and selective palladium-catalyzed cross-coupling reactions (Scheme 1).[‌1‌‌5‌] The first examples were reported in the period 1976–1978 by Eaborn,[‌6‌] Kosugi,[‌7‌‌9‌] and Stille,[‌10‌] which was immediately followed by systematic work by the group of Stille that established the scope and the basic aspects of the mechanism of this reaction.[‌11‌]

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