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2.3.1.3.2.1 Coupling of Thiols with Vinyl Halides

DOI: 10.1055/sos-SD-208-00234

Eichman, C. C.; Stambuli, J. P.Science of Synthesis: Cross Coupling and Heck-Type Reactions, (20132379.

There are very few methods for the palladium-catalyzed coupling of vinyl halides with thiols; however, 1-bromo-2-phenylethene (56) undergoes coupling with benzenethiol to give (E/Z)-2-phenylvinyl sulfide 57 with conservation of starting alkene geometry (Scheme 18).[‌53‌]

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