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1.1.4 Diversity of Multicomponent Reactions

DOI: 10.1055/sos-SD-210-00002

Müller, T. J. J.Science of Synthesis: Multicomponent Reactions, (2014123.

Multicomponent reactions are often associated with diversity-oriented synthesis. This concept, introduced by Schreiber,[‌82‌,‌83‌] points out the structural dimension accessible by a specific reaction or sequence of reactions. The ultimate goal is definitely accessing the utmost flexibility with as many functional variations as possible and with as few synthetic strategies as necessary. Ideally, each step involved should generate structural complexity. This approach is particularly advantageous for lead development in pharmaceutical chemistry and agrochemistry,[‌19‌‌22‌,‌84‌] but also increasingly important with respect to functional π-systems[‌24‌,‌25‌] in future molecular photonics, electronics, and magnetics.

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