Science of Synthesis

Vanden Eynde, J. J.; Mayence, A., Science of Synthesis: Multicomponent Reactions, (2014) 1, 91.

Faced with an increasing demand for novel drug candidates and novel chemicals in general, there is considerable current interest in methodologies associated with combinatorial chemistry. Solid-phase synthesis and derived protocols are often used to simplify workup procedures and increase the purity of target compounds.

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References