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DOI: 10.1055/sos-SD-210-00051

Vanden Eynde, J. J.; Mayence, A.Science of Synthesis: Multicomponent Reactions, (2014191.

Faced with an increasing demand for novel drug candidates and novel chemicals in general, there is considerable current interest in methodologies associated with combinatorial chemistry. Solid-phase synthesis and derived protocols are often used to simplify workup procedures and increase the purity of target compounds.

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