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Please login to access the full content or check if you have access via2.5.5.2.1 Prins Reaction
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Kaposi, M.; Witt, J.; Cokoja, M.; Kühn, F. E., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2014) 2, 295.
Acid-catalyzed reactions of alkenes with aldehydes are generally referred to as the Prins reaction (Scheme 5). When this reaction is carried out thermally, in the absence of a catalyst, the products are usually those expected from ene reactions, which are discussed in Section 2.5.5.2.2. Depending on the reaction conditions, the major products are 1,3-dioxanes 16, 1,3-glycols 14, or unsaturated alcohols 15 (ene product).[24]
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Meeeee 8 Meeee Meeeeeee ee Meeeeeee eeee Meeeeeeeeeeeeeee Meeee (8,8-Me-eeee-eeeeeeeeeeee)eeeeeeeeeeeeee ee Meeeeeee[88]
| Me8 | Meeeeeeeee | Meeee (%) | Mee |
|---|---|---|---|
| Me | 88 °M, 88 e | 88 | [88] |
| 8-Mee | 88 °M, 88 e | 88 | [88] |
| 8-MeMM8M8 | 88 °M, 8 e | 88 | [88] |
| 8-MeM8M8 | 888 °M, 88 e | 88 | [88] |
| 8-MeMM8M8 | 888 °M, 88 e | 88 | [88] |
| 8-eeeeeee | 88 °M, 88 e | 88 | [88] |
Meeeeeeeeeee Meeeeeeee
8-Meee-8,8-eeeeeeee 88; Meeeeee Meeeeeeee:[88]
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References
| [24] | Meeee, M. M.; Meeeeeeee, M. M., Meeeeeeee, (8888), 888. |
| [25] | Meee, M.; Möeee, M., Meeeeeeee, (8888), 8888. |
| [26] | e. Meeeeee, M.; Meeee, M.; Meeeeeeeee, M.; Meeeeee, M.-M.; Meeeee, M., Meeeeeeeeeeeeee, (8888) 88, 8888. |
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