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DOI: 10.1055/sos-SD-213-00165

Kaposi, M.; Witt, J.; Cokoja, M.; Kühn, F. E.Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (20142295.

Acid-catalyzed reactions of alkenes with aldehydes are generally referred to as the Prins reaction (Scheme 5). When this reaction is carried out thermally, in the absence of a catalyst, the products are usually those expected from ene reactions, which are discussed in Section Depending on the reaction conditions, the major products are 1,3-dioxanes 16, 1,3-glycols 14, or unsaturated alcohols 15 (ene product).[‌24‌]

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