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2.5.7.5.4 Reactions of Alkenes with Halomethyleniminium Salts

DOI: 10.1055/sos-SD-213-00191

Zhang, N.; Dong, D.Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (20142342.

The reaction of simple alkenes bearing alkyl groups with Vilsmeier reagents are complex because of side products arising from iminoalkylation or migration of the C=C bond. However, monoformylation of the alkenes occurs when migration of the double bonds is restricted (Scheme 9).[‌24‌‌27‌]

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