Science of Synthesis

Zhang, N.; Dong, D., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2014) 2, 342.

The reaction of simple alkenes bearing alkyl groups with Vilsmeier reagents are complex because of side products arising from iminoalkylation or migration of the C=C bond. However, monoformylation of the alkenes occurs when migration of the double bonds is restricted (‌Scheme 9‌).[‌24‌–‌27‌]

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Meeeeeeeeeeeee [‌88‌, M8 = (M)-MM=MMMe]; Meeeeee Meeeeeeee:[‌88‌]

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References