Science of Synthesis

Faber, K.; Glueck, S. M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 461.

l-Arabinose isomerase (EC 5.3.1.4) catalyzes the reversible isomerization of l-arabinose to give l-ribulose. Furthermore, this enzyme is also able to convert d-galactose into d-tagatose and is thus also referred to as d-galactose isomerase (‌Scheme 34‌).[‌95‌]

‌Meeeee 88‌ Meeeeee Meeeeeeeee ee e-Meeeeeeee Meeeeeeee[‌88‌]

Meeeeee eeeeee-eeeeee eeeeeeeeee, eeeeee eeee eeeeeeeee eeeeeee, eeee eeee eeeeeeee eee eeeeeeeeeeeee eeeeeeeeeeeee.[‌88‌–‌88‌] Mee eeeeeeee ee eeeeeeee eeeee eeee, eeee ee Me8+, Me8+, Me8+, Me8+, eee Me8+ eeeeeeeee eee eeeeeeeeeeeee eeeeeeee.[‌88‌–‌888‌] e-Meeeeeeee eeeeeeeee eeeeeeeeee e eeeeeeee eeeeee ee eeeeee ee eeeeeeee ee eee eeeeeee eeeeeeeeee (‌Meeee 8‌).[‌888‌–‌888‌]

‌Meeee 8‌ Meeeeeeee Meeee ee e-Meeeeeeee Meeeeeeee eeee Meeeeeeee Meeeeee[‌888‌–‌888‌]

e Mee eeeeeeeeee ee eeeeee eee ‌Meeeee 88‌.

e Meeeeeee eeeeeeee; eee eee eeee eeee eeeeeeeeeeeee ee eeeeee.

e Meeeeeee eeeeeeeeee eeeeeeeee ee % eeeeeeee ee eee eeeeeee eeeeeeeee e-eeeeeeeee ee e-eeeeeeeee (888%), eeeeeeeeeeee.

e-Meeeeeeee eeeeeeeee ee eeeeeee ee eeeeeeeeeeeeeeee eeeeeeeee eee eee eeeee-eeeee eeeeeeeeee ee e-eeeeeeee, e eee-eeeeeee eeeeeeeee, eeeee eeeeeeee eeeeee eeeeeeeeee eeeeeeeee ee eeeeeee. Meeeee eeee, e-eeeeeeee eeeee eeeeeee eeeeee eeeeeeee eeee ee eeeeeeeeeee, eeeeeeeee, eeee-eeeeeeeee, eeeeeeeeeee, eee eeeeeeeeee eeeeeeeeee eee ee eeeeeeee eeeeee, eee ee eeee e eeeeeeeee eeeeee ee eee eeeeeeeeeeeeee eee eeee eeeeeeeeee. Mee eeeeeeeeeeee eeeeeeee eee eee eeeeeeeee eeeeee eeee e-eeeeeeeee ee eeeeeeeee, eeeee ee eeeeeeeee ee e-eeeeeeeee eeeeeeeee eeee eee eeeeeee e-eeeeeeee. Meee eeeeeeeeee e eeeeeeeee eeeeeeeeeee ee eeeeeeee eeeeeee, eeeee eee eeeeeeeeeee ee eeeeeee eeeeeeeee, eeee ee eee eeee eee eeeee eeeeeeee eeeeeeeeee (eeeeee eeee), eeeeeeeeeee ee eeeeeeeee eee eeeee eeeeeeeee, ee eeee ee eeee eeeeee eeeeee (eeeeeeeee eeeeeee). Meeeeeeeeee eeeeeeeeeeee e-eeeeeeeee eeeeeeeee eeee Meeeeeeeeee eeeeeeeeeeeeeeeeee ee eeeeeee ee e eeeeee-eee eeeeeeeeee ee eeeeeee 888 e · M−8 eeeeeeee eeee 888 e · M−8 e-eeeeeeeee.[‌88‌,‌888‌]

Mee eeeeeeeeeeee ee e-eeeeeeee eee eeee eeeeeee eeeeeeee ee eee eeeeeeee ee eeeee eeee eeeee ee e-eeeeeeeee eeeeeeeee eeeeeee eeee M. eeeeeeeeeeeeeeeeeee. M eeeee ee 888 e · M−8 e-eeeeeeee eee eeeeeeee eeee 888 e · M−8 e-eeeeeeeee, eeeeeeeeeeeee ee e eeeeeeeeee eeee ee 88.8 e · M−8 · e−8.[‌888‌]

Me e eeeeee-eeee eeeeeee, e-eeeeeeee ee eeeeeeee eeee eee eeeeeeeeeee eeeeeeee eeeeeeee eeeeeee. Meeeeeeeeeee ee β-e-eeeeeeeeeeeee eee e-eeeeeeeee eeeeeeeee ee M. eeee eeeeee eee eeeeeeeeee ee eee eeeeeeeeeeee eee eeeeeeeeee eeeeeeeeeeeee ee ee eeeeeeeee ee eee eee ee eeeeee e-eeeeeeee (‌Meeeee 88‌).[‌888‌]

‌Meeeee 88‌ Meeeeeeeee ee Meeeeee eeee e-Meeeeeee Meeee β-e-Meeeeeeeeeeee eee e-Meeeeeeee Meeeeeeee[‌888‌]

Meeeeee eeeeeee ee eee eeeeeeeeeeeeeeee eeeeeeeeeee ee e-eeeeeeeee eeeeeeeee ee eee eeeeeeeeee ee e-eeeeee, e eeee eee eeeeeeeee eeeee eeee ee eeeeeeeee eee eeeeeeeee eeeee. e-Meeeeeeee (888 e · M−8) ee eeeeeeeee eeee e-eeeeee (888 e · M−8) ee e eee-eeeeee eeeeee ee eeeeeeeee e-eeeeeeeee eeeeeeeee eee eeeeeee 8-eeeeeeeee eeeeeeeee eeee M. eeeeeeeeeeeeeeeeeee.[‌888‌,‌888‌]

Meeeeeeeeeee Meeeeeeee

Meeeeeeeeeeee ee eee Meeeeeeee Meeeeeeeeee ee e-Meeeeeeee Meeeeeeee eeee M. eeeeeeeeeeeeeeeeee (‌Meeee 8‌); Meeeeee Meeeeeeee:[‌888‌]

Meeeeeeee eeee eeeeeee eee ee 88 °M ee 88 eM MMMM eeeeee (eM 8.8) eee 88 eee eeeee e eeeeeeeee eeeeeeeeeeeee ee 88 eM. Mee eeeeeeeeeeeeee ee eee eeeeee eeeeeeee ee e-eeeeeeeee, e-eeeeeeeee, e-eeeeee, e-eeeeee, e-eeeeee, e-eeeeee, eee e-eeeeeee eeee eeeeeeeeee eeeee eee eeeeeeeeeeee eeeeeeee-eeeeeeeee eeeeee eeee eeeeeeeeeeeeeeeeee eeeeeeeeeee ee 888 ee. Mee eeeeeeeeeeeeee ee e-eeeeeeee eee e-eeeeeeeee eeee eeeeeeeeee ee MMMM eeeeeeee.

e-Meeeeeee (‌88‌); Meeeeee Meeeeeeee ee e Meeeee-Mee Meeeeeeeee:[‌888‌]

e-Meeeeeeee eeeeeeeee eeeeeeeee ee eeeeeeee eeeee eee eeeeee ee e eeeeeee eee eeee eee eeee eeeeeeee eeeeeeeeee. Mee eeeeeee eeeeee ee eee eeeeeee eee 88 eM eeee e eeeeee eee eeeeeeee ee 888 eee 88 ee, eeeeeeeeeeee. M eeeeeeeee eeee ee 88 eM Meee-MMe eeeeee (eM 8.8) eee eee eeee eee eeeeeee ee e eeee eeee ee 8.8 eM · e−8 eeeee e eeeeeeeeeee eeee. Mee eeeeeeee eeeeeeeeeee eee eeeeeeeeee ee 88 °M eeeee e eeeee eeeeeeeeee. Mee eeeeeeeeee eeeeeeeee, eeeeee (888 eM) eeeeeeeeee eeeeeeeee (888 e · M−8) eee eeeeeeeeeeee eee eee eeeee eeee eee eeeeeee ee ee eeeeeeee eeeeeeeee. Mee eeeeeeeeee eeeeeeeee eeeeeeeee, eeee eee eeeeeeeee eee eeee eee eeeeee eeeeeeeeee eeeeeeeee (888 e · M−8) ee eee eeeeeeeee eee eeeeeeee eee 88 e eee eeeeeeee eeee eeeee eeeeee eeeee 88 e. Meeeeeee ee eeeeeeee eeeeeeeeeeeee eee eeeeeeeee ee e eeeeeeeeeeeeeeeee ee 888 ee eeeee eee eeeeeeeeeeee eeeeeeee-eeeeeeeee eeeeee. Meeeeeee eee eeeeeeeee eeeeeeeeeeeeee eeee eeeeeeeeee ee MMMM eeeeeeee eeee e eeeeeeeeee eeeee eeeeeeee.

e-Meeeeeee (‌88‌); Meeeeee Meeeeeeee eee eee Meeeee-Meee Meeeeeeeee eeee Meeeeee:[‌888‌]

Mee eeeeeeeeeeeeeeeee eeeeee (888 eM) eeeeeeeee eeeeeee (88 e · M−8), MeMe8 (88 eM), MeMe8 (8 eM), 888 eM eeeeeeeee eeeeee (eM 8.8), eeeeee (888 eM), eee M. eeee-MM eeeee (8.8 e ee eee eeeee eeeeeeeee β-e-eeeeeeeeeeeee eee e-eeeeeeeee eeeeeeeee, eeeeeeeeeee eeee 888 eM ee eeeeeeeeeeee eeeee). Mee eeeeeeee eeeeeeeeee eeee 88 °M eee 88 e (888 eee). Meeeeee (8.8 eM) eeee eeeee ee 8 e eeeeeeeee eee MMMM eeeeeeee.

References