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DOI: 10.1055/sos-SD-216-00052

Ewing, T. A.; Fraaije, M. W.; van Berkel, W. J. H.Science of Synthesis: Biocatalysis in Organic Synthesis, (20153173.

Pyranose 2-oxidase (P2O, EC is a GMC-type (glucose–methanol–choline) oxidase. The enzyme catalyzes the oxidation of d-glucose and other aldopyranoses at the C2 position, yielding the corresponding ketoaldoses. Pyranose 2-oxidase has been isolated from a number of wood-degrading white-rot basidiomycetes.[‌102‌] The native enzyme is a homotetramer of 280 kDa, with each subunit containing one molecule of flavin adenine dinucleotide (FAD), which is covalently linked to a histidine residue.[‌103‌]

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