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Please login or sign up for a free trial to access the full content. Ring-Closing Metathesis–Semireduction for the Construction of E-Alkenes

DOI: 10.1055/sos-SD-222-00346

Lee, D.; Reddy Sabbasani, V.Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (20162661.

In addition to the successful implementation of Z-selective macrocycle synthesis in various natural product syntheses via ring-closing alkyne metathesis–semihydrogenation, procedures for the construction of the complementary macrocyclic E-alkenes have been developed, although exploited to a lesser extent by far.[‌229‌,‌230‌]

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