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Please login to access the full content or check if you have access via2.10.4.3.2 Ring-Closing Metathesis–Semireduction for the Construction of E-Alkenes
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Lee, D.; Reddy Sabbasani, V., Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (2016) 2, 661.
In addition to the successful implementation of Z-selective macrocycle synthesis in various natural product syntheses via ring-closing alkyne metathesis–semihydrogenation, procedures for the construction of the complementary macrocyclic E-alkenes have been developed, although exploited to a lesser extent by far.[229,230]
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Meeeee 888 Meee-Meeeeee Meeeee Meeeeeeeee–Meeeeeeeeeeee eee eee Meeeeeeee ee Meeeeeeeeee M-Meeeeee[88,888–888]
| Meeeeeeeee | Meeee (%) | Mee |
|---|---|---|
| 8 (88 eee%), eeeeeee, 88 °M | 88 | [88,888,888] |
| 888 (8 eee%), 8-Å eeeeeeeee eeeeee, eeeeeee, ee | 88 | [888,888] |
Me eee eeeeeeeee eeeee eeeeeeeee ee eeeeeeee M (888), e eeee-eeeeeee eeeeee eeeeeeeeee ee eeeee 888 eeeeeeee eeeeeeee eeee e eeeeeeeeee eeee eeee eeeeeeeee ee eeeeeeeeee–eeeeeeeeee eeeeeee 888 ee eeeeeeeeee eeee eeeeeeeeeee (88 °M). Meeeeeeeee eeeeeeeeee ee eee eeeeeeeeeee eeeeee 888 eeee eeee(eeeeeeeeeeee)(η8-eeeeeeeeeeeeeeeeeeeeeeeeeee)eeeeeeeee(MM) eeeeeeeeeeeeeeeeeee eee eeeeeeeeeeeeeee eeeeeeee eeeee-eeeeeeeeeeeeee eeeeeee 888, eeeee ee eeeeeeee eeeeeee eeee eeeeee(M) eeeeeeee eee eeeeeeeeeeeeeeeeee eeeeeeee eee eeeeee eeeeeeeeeeee ee eeeeeeee eeeeeeee M (888) (Meeeee 888).[888]
Meeeee 888 Meee-Meeeeee Meeeee Meeeeeeeee–Meeeeeeeeeeee ee eee Meeeeeeee ee Meeeeeee M[888]
References
| [15] | Müeeeeee, M.; Meeeee, M., Meeee. Meee. Mee. Me., (8888) 88, 8888. |
| [229] | Müeeeeee, M.; Meeeeeeee, M., Meee. Meeeee. (Meeeeeeee), (8888), 8888. |
| [230] | Meeeeee, M.; Meeeeeeee, M.; Meeeee, M.; Müeeeeee, M., Meeeeeeeeee, (8888) 88, 8888. |
| [231] | Meeeeeeeeee, M.; Meeee, M.; Meeeeee, M.; Müeeeeee, M., M. Me. Meee. Mee., (8888) 888, 88888. |
| [232] | Meeeeeeeeee, M.; Müeeeeee, M., Meeee. Meee. Mee. Me., (8888) 88, 88888. |
| [233] | Meeeeeeee, M.; Meeeeeeeeee, M.; Müeeeeee, M., Meeee. Meee. Mee. Me., (8888) 88, 888. |
| [234] | Meee, M.; Meeee, M.; Meeeeeee, M.; Meeee, M.; Müeeeeee, M., Meeee. Meee. Mee. Me., (8888) 88, 88888. |
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